دورية أكاديمية

Novel simultaneous combination chemical thrombolysis/rheolytic thrombectomy therapy for acute critical limb ischemia: The power‐pulse spray technique

التفاصيل البيبلوغرافية
العنوان: Novel simultaneous combination chemical thrombolysis/rheolytic thrombectomy therapy for acute critical limb ischemia: The power‐pulse spray technique
المؤلفون: Allie, David E., Hebert, Chris J., Lirtzman, Mitchell D., Wyatt, Charles H., Keller, V. Antoine, Khan, Mohamed H., Barker, Esmond A., McElderry, Michael W., Khan, Muhammad A., Fail, Peter S., Stagg, Samuel J., Mitran, Elena V., Chaisson, Gary, Allie, Sonja D., Allie, Adam A., Walker, Craig M.
المصدر: Catheterization and Cardiovascular Interventions ; volume 63, issue 4, page 512-522 ; ISSN 1522-1946 1522-726X
بيانات النشر: Wiley
سنة النشر: 2004
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: The novel power‐pulse spray (P‐PS) technique maximizes and combines the advantages and minimizes the disadvantages of both chemical thrombolysis (CT) and rheolytic thrombectomy (RT). Forty‐nine consecutive patients with iliofemoral thrombotic occlusion were treated via P‐PS technique. Using a 6 Fr RT catheter, saline prime was exchanged for thrombolytic solution [group 1, 10–20 mg tenecteplase (TNK)/50 cc saline, n = 25; group 2, 1,000,000 urokinase (UK)/50 cc saline, n = 24]. The outflow port was closed, then the catheter was advanced at 1 mm increments while pulsing lytic agent. After 30‐min lysis time, RT and definitive treatment of the underlying stenosis were performed. Procedure success was 23/25 (92%) and 22/24 (91.6%) for group 1 and 2, respectively. The mean total procedure time was 72 and 75 min in group 1 and 2, respectively. Thirty‐day limb salvage was 91% in both groups. There were no major surgical complications. The P‐PS technique is safe and effective using either UK or TNK, offering several potential advantages over monotherapy, including more rapid revascularization, decreases systemic lytic exposure and bleeding complications while facilitating both CT and RT capacity and efficacy. Catheter Cardiovasc Interv 2004;63:512–522. © 2004 Wiley‐Liss, Inc.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1002/ccd.20216
الإتاحة: https://doi.org/10.1002/ccd.20216Test
حقوق: http://onlinelibrary.wiley.com/termsAndConditions#vorTest
رقم الانضمام: edsbas.1F500B9E
قاعدة البيانات: BASE