دورية أكاديمية

Prediction of Pregnancy-Associated Hypertension Using a Scoring System: A Multicenter Cohort Study

التفاصيل البيبلوغرافية
العنوان: Prediction of Pregnancy-Associated Hypertension Using a Scoring System: A Multicenter Cohort Study
المؤلفون: Yun Sung Jo, Woo Jeng Kim, Sae Kyung Choi, Su Mi Kim, Jae Eun Shin, Ki Cheol Kil, Yeon Hee Kim, Jeong Ha Wie, Han Wool Kim, Subeen Hong, Hyun Sun Ko
المصدر: Life; Volume 13; Issue 6; Pages: 1330
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2023
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: pregnancy-associated hypertension, prediction, risk, scoring
جغرافية الموضوع: agris
الوصف: This study aimed to develop an early pregnancy risk scoring model for pregnancy-associated hypertension (PAH) based on maternal pre-pregnancy characteristics, such as mean arterial pressure (MAP), pregnancy-associated plasma protein-A (PAPP-A) or neither. The perinatal databases of seven hospitals from January 2009 to December 2020 were randomly divided into a training set and a test set at a ratio of 70:30. The data of a total pregnant restricted population (women not taking aspirin during pregnancy) were analyzed separately. Three models (model 1, pre-pregnancy factors only; model 2, adding MAP; model 3, adding MAP and PAPP-A) and the American College of Obstetricians and Gynecologists (ACOG) risk factors model were compared. A total of 2840 (8.11%) and 1550 (3.3%) women subsequently developed PAH and preterm PAH, respectively. Performances of models 2 and 3 with areas under the curve (AUC) over 0.82 in both total population and restricted population were superior to those of model 1 (with AUCs of 0.75 and 0.748, respectively) and the ACOG risk model (with AUCs of 0.66 and 0.66) for predicting PAH and preterm PAH. The final scoring system with model 2 for predicting PAH and preterm PAH showed moderate to good performance (AUCs of 0.78 and 0.79, respectively) in the test set. “A risk scoring model for PAH and preterm PAH with pre-pregnancy factors and MAP showed moderate to high performances. Further prospective studies for validating this scoring model with biomarkers and uterine artery Doppler or without them might be required”.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
العلاقة: Medical Research; https://dx.doi.org/10.3390/life13061330Test
DOI: 10.3390/life13061330
الإتاحة: https://doi.org/10.3390/life13061330Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.1F4800E5
قاعدة البيانات: BASE