دورية أكاديمية
Soft subdermal implant capable of wireless battery charging and programmable controls for applications in optogenetics
| العنوان: | Soft subdermal implant capable of wireless battery charging and programmable controls for applications in optogenetics |
|---|---|
| المؤلفون: | Kim, Choong Yeon, Ku, Min Jeong, Qazi, Raza, Nam, Hong Jae, Park, Jong Woo, Nam, Kum Seok, Oh, Shane, Kang, Inho, Jang, Jae-Hyung, Kim, Wha Young, Kim, Jeong-Hoon, Jeong, Jae-Woong |
| المساهمون: | National Research Foundation of Korea, KAIST |
| المصدر: | Nature Communications ; volume 12, issue 1 ; ISSN 2041-1723 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary |
| الوصف: | Optogenetics is a powerful technique that allows target-specific spatiotemporal manipulation of neuronal activity for dissection of neural circuits and therapeutic interventions. Recent advances in wireless optogenetics technologies have enabled investigation of brain circuits in more natural conditions by releasing animals from tethered optical fibers. However, current wireless implants, which are largely based on battery-powered or battery-free designs, still limit the full potential of in vivo optogenetics in freely moving animals by requiring intermittent battery replacement or a special, bulky wireless power transfer system for continuous device operation, respectively. To address these limitations, here we present a wirelessly rechargeable, fully implantable, soft optoelectronic system that can be remotely and selectively controlled using a smartphone. Combining advantageous features of both battery-powered and battery-free designs, this device system enables seamless full implantation into animals, reliable ubiquitous operation, and intervention-free wireless charging, all of which are desired for chronic in vivo optogenetics. Successful demonstration of the unique capabilities of this device in freely behaving rats forecasts its broad and practical utilities in various neuroscience research and clinical applications. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1038/s41467-020-20803-y |
| الإتاحة: | https://doi.org/10.1038/s41467-020-20803-yTest https://www.nature.com/articles/s41467-020-20803-y.pdfTest https://www.nature.com/articles/s41467-020-20803-yTest |
| حقوق: | https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: | edsbas.1DA84391 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41467-020-20803-y |
|---|