دورية أكاديمية
Risk factors for Gram-negative bacterial infection of cardiovascular implantable electronic devices: multicentre observational study (CarDINe Study).
| العنوان: | Risk factors for Gram-negative bacterial infection of cardiovascular implantable electronic devices: multicentre observational study (CarDINe Study). |
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| المؤلفون: | Pascale, R., Toschi, A., Aslan, A.T., Massaro, G., Maccaro, A., Fabbricatore, D., Dell'Aquila, A., Ripa, M., Işık, M.E., Kızmaz, Y.U., Iacopino, S., Camici, M., Perna, F., Akinosoglou, K., Karruli, A., Papadimitriou-Olivgeris, M., Kayaaslan, B., Bilir, Y.A., Evren Özcan, E., Turan, O.E., Işık, M.C., Pérez-Rodríguez, M.T., Yagüe, B.L., Quirós, A.M., Yılmaz, M., Petersdorf, S., De Potter, T., Durante-Mangoni, E., Akova, M., Curnis, A., Gibertoni, D., Diemberger, I., Scudeller, L., Viale, P., Giannella, M. |
| المساهمون: | CarDINe Study Group, Caroccia, N., Fanì, F., Arbizzani, F., Ramanathan, R., Scarpellini, P., Marzi, A., Mazzone, P., Placentino, F., Sammarini, G., Tenti, E., Leventopulos, G., Domenichini, G., Şahin, M., Suárez-Varela, M., Villegas, E.G. |
| المصدر: | International journal of antimicrobial agents, vol. 61, no. 3, pp. 106734 |
| سنة النشر: | 2023 |
| المجموعة: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| مصطلحات موضوعية: | Humans, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography/adverse effects, Positron Emission Tomography Computed Tomography/methods, Defibrillators, Implantable/adverse effects, Implantable/microbiology, Retrospective Studies, Radiopharmaceuticals, Risk Factors, Cardiovascular Infections, Gram-Negative Bacterial Infections/epidemiology, Gram-Negative Bacterial Infections/complications, Obesity, Prosthesis-Related Infections/epidemiology, Prosthesis-Related Infections/diagnosis, CIED infection, Cardiovascular implantable electronic devices, Endocarditis, FDG PET/CT, Gram-negative |
| الوصف: | Infections of cardiovascular implantable electronic devices (CIED) are mainly due to Gram-positive bacteria (GPB). Data about Gram-negative bacteria CIED (GNB-CIED) infections are limited. This study aimed to investigate risk factors, clinical and diagnostic characteristics, and outcome of patients with GNB-CIED. A multicentre, international, retrospective, case-control-control study was performed on patients undergoing CIED implantation from 2015 to 2019 in 17 centres across Europe. For each patient diagnosed with GNB-CIED, one matching control with GPB-CIED infection and two matching controls without infection were selected. A total of 236 patients were enrolled: 59 with GNB-CIED infection, 59 with GPB-CIED infection and 118 without infection. No between-group differences were found regarding clinical presentation, diagnostic and therapeutic management. A trend toward a higher rate of fluorodeoxyglucose positron emission computed tomography (FDG PET/CT) positivity was observed among patients with GNB than in those with GPB-CIED infection (85.7% vs. 66.7%; P = 0.208). Risk factors for GNB-CIED infection were Charlson Comorbidity Index Score (relative risk reduction, RRR = 1.211; P = 0.011), obesity (RRR = 5.122; P = 0.008), ventricular-pacing ventricular-sensing inhibited-response pacemaker implantation (RRR = 3.027; P = 0.006) and right subclavian vein site of implantation (RRR = 5.014; P = 0.004). At 180-day survival analysis, GNB-CIED infection was associated with increased mortality risk (HR = 1.842; P = 0.067). Obesity, high number of comorbidities and right subclavian vein implantation site were associated with increased risk of GNB-CIED infection. A prompt therapeutic intervention that may be guided using FDG PET/CT is suggested in patients with GNB-CIED infection, considering the poorer outcome observed in this group. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0924-8579 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36690123; info:eu-repo/semantics/altIdentifier/eissn/1872-7913; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_931BAB18E7639; https://serval.unil.ch/notice/serval:BIB_931BAB18E763Test; urn:issn:0924-8579; https://serval.unil.ch/resource/serval:BIB_931BAB18E763.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_931BAB18E7639Test |
| DOI: | 10.1016/j.ijantimicag.2023.106734 |
| الإتاحة: | https://doi.org/10.1016/j.ijantimicag.2023.106734Test https://serval.unil.ch/notice/serval:BIB_931BAB18E763Test https://serval.unil.ch/resource/serval:BIB_931BAB18E763.P001/REF.pdfTest http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_931BAB18E7639Test |
| حقوق: | info:eu-repo/semantics/openAccess ; CC BY-NC-ND 4.0 ; https://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: | edsbas.1D2A1928 |
| قاعدة البيانات: | BASE |
| تدمد: | 09248579 |
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| DOI: | 10.1016/j.ijantimicag.2023.106734 |