دورية أكاديمية
Optimizing eligibility criteria and clinical trial conduct to enhance clinical trial participation for primary brain tumor patients
| العنوان: | Optimizing eligibility criteria and clinical trial conduct to enhance clinical trial participation for primary brain tumor patients |
|---|---|
| المؤلفون: | Lee, Eudocia Q, Weller, Michael, Sul, Joohee, Bagley, Stephen J, Sahebjam, Solmaz, van den Bent, Martin, Ahluwalia, Manmeet, Campian, Jian L, Galanis, Evanthia, Gilbert, Mark R, Holdhoff, Matthias, Lesser, Glenn J, Lieberman, Frank S, Mehta, Minesh P, Penas-Prado, Marta, Schreck, Karisa C, Strowd, Roy E, Vogelbaum, Michael A, Walbert, Tobias, Chang, Susan M, Nabors, L B, Grossman, Stuart, Reardon, David A, Wen, Patrick Y |
| المصدر: | Neurosurgery Articles |
| بيانات النشر: | Henry Ford Health Scholarly Commons |
| سنة النشر: | 2020 |
| المجموعة: | Henry Ford Health System Scholarly Commons |
| الوصف: | Building on an initiative to enhance clinical trial participation involving the Society for Neuro-Oncology (SNO), the Response Assessment in Neuro-Oncology (RANO) Working Group, patient advocacy groups, clinical trial cooperative groups, and other partners, we evaluate the impact of eligibility criteria and trial conduct on neuro-oncology clinical trial participation. Clinical trials often carry forward eligibility criteria from prior studies that may be overly restrictive, unnecessary, and needlessly limit patient accrual. Inclusion and exclusion criteria should be evaluated based on the goals and design of the study and whether they impact patient safety and/or treatment efficacy. In addition, we evaluate clinical trial conduct as barriers to accrual and discuss strategies to minimize such barriers for neuro-oncology trials. |
| نوع الوثيقة: | text |
| اللغة: | unknown |
| العلاقة: | https://scholarlycommons.henryford.com/neurosurgery_articles/326Test; http://sfxhosted.exlibrisgroup.com/hfhs?sid=Entrez:PubMed&id=pmid:31974566Test |
| الإتاحة: | https://scholarlycommons.henryford.com/neurosurgery_articles/326Test http://sfxhosted.exlibrisgroup.com/hfhs?sid=Entrez:PubMed&id=pmid:31974566Test |
| رقم الانضمام: | edsbas.1C3D77F1 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |