التفاصيل البيبلوغرافية
العنوان: |
Drug delivery methods for cancer immunotherapy |
المؤلفون: |
Pérez-Herrero, Edgar, Lanier, Olivia L., Krishnan, Neha, D’Andrea, Abby, Peppas, Nicholas A. |
المساهمون: |
Universidad de La Laguna, National Institutes of Health, Cockrell School of Engineering, University of Texas at Austin, UT-Portugal Collaborative Research Program, The University of Texas at Austin Provost Early Career Postdoctoral Fellowship Program, Universidad de la Laguna |
المصدر: |
Drug Delivery and Translational Research ; volume 14, issue 1, page 30-61 ; ISSN 2190-393X 2190-3948 |
بيانات النشر: |
Springer Science and Business Media LLC |
سنة النشر: |
2023 |
مصطلحات موضوعية: |
Pharmaceutical Science |
الوصف: |
Despite the fact that numerous immunotherapy-based drugs have been approved by the FDA for the treatment of primary and metastatic tumors, only a small proportion of the population can benefit from them because of primary and acquired resistances. Moreover, the translation of immunotherapy from the bench to the clinical practice is being challenging because of the short half-lives of the involved molecules, the difficulties to accomplish their delivery to the target sites, and some serious adverse effects that are being associated with these approaches. The emergence of drug delivery vehicles in the field of immunotherapy is helping to overcome these difficulties and limitations and this review describes how, providing some illustrative examples. Moreover, this article provides an exhaustive review of the studies that have been published to date on the particular case of hematological cancers. Graphical Abstract (Created with BioRender) |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1007/s13346-023-01405-9 |
DOI: |
10.1007/s13346-023-01405-9.pdf |
DOI: |
10.1007/s13346-023-01405-9/fulltext.html |
الإتاحة: |
https://doi.org/10.1007/s13346-023-01405-9Test |
حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
رقم الانضمام: |
edsbas.1C3144E4 |
قاعدة البيانات: |
BASE |