دورية أكاديمية
A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain and emotional valence
| العنوان: | A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain and emotional valence |
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| المؤلفون: | Christopher H. Chen, Leannah N. Newman, Amanda P. Stark, Katherine E. Bond, Dawei Zhang, Stefano Nardone, Charles Vanderberg, Naeem Nadaf, Kefiloe Mutume, Zhiyi Yao, Isabella Flaquer, Bradford B. Lowell, Evan Macosko, Wade G. Regehr |
| سنة النشر: | 2022 |
| المجموعة: | Zenodo |
| مصطلحات موضوعية: | Cerebellum, Parabrachial Nuclei, Purkinje cell, Deep Cerebellar Nuclei |
| الوصف: | OVERVIEW The following README contains: i) the raw count matrix relative to all nuclei of the dataset, called “filtered_feature_bc_matrix”; ii) the cell cycle genes lists (G2/M and S phase specific markers) named “cycle_gene”; iii) the markers gene lists used to generate the Dot Plots for the All_cells and Neuronal clustering (glial and neuronal markers); iv) the instruction to set up an R environment (R version 4.1.2) and to install R Studio on a Windows/macOS operative systems; iii) the instructions to install Seurat 3.2.3 along with all its dependencies; iv) the software code used to generate all the plots and figure as showed in the manuscript. SYSTEM REQUIREMENTS The following analysis can be performed on a standard computer with sufficient RAM to support the in-memory operation required by Seurat 3.2.3. The installation of Seurat 3.2.3 and all its dependencies have been tested on both Windows (version 10 64-bit ) and macOS (Big Sur version 11.6.1) operating systems. ALL PACKAGES and DEPENDENCIES R version 4.1.2 (2021-11-01) Platform: x86_64-apple-darwin17.0 (64-bit) Running under: macOS Monterey 12.2.1 Matrix products: default LAPACK: /Library/Frameworks/R.framework/Versions/4.1/Resources/lib/libRlapack.dylib locale: [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8 attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] dplyr_1.0.8 scales_1.1.1 RColorBrewer_1.1-2 viridis_0.6.2 viridisLite_0.4.0 ggplot2_3.3.5 Matrix_1.3-4 [8] biomaRt_2.50.3 Seurat_3.2.3 loaded via a namespace (and not attached): [1] BiocFileCache_2.2.1 plyr_1.8.6 igraph_1.2.11 lazyeval_0.2.2 splines_4.1.2 [6] listenv_0.8.0 scattermore_0.8 GenomeInfoDb_1.30.1 digest_0.6.29 htmltools_0.5.2 [11] fansi_1.0.2 magrittr_2.0.3 memoise_2.0.1 tensor_1.5 cluster_2.1.2 [16] ROCR_1.0-11 limma_3.50.1 remotes_2.4.2 globals_0.14.0 Biostrings_2.62.0 [21] matrixStats_0.61.0 prettyunits_1.1.1 colorspace_2.0-3 blob_1.2.2 rappdirs_0.3.3 [26] ggrepel_0.9.1 crayon_1.5.0 RCurl_1.98-1.6 ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English, Old (ca.450-1100) |
| العلاقة: | https://zenodo.org/record/6653204Test; https://doi.org/10.5281/zenodo.6653204Test; oai:zenodo.org:6653204 |
| DOI: | 10.5281/zenodo.6653204 |
| الإتاحة: | https://doi.org/10.5281/zenodo.6653204Test https://doi.org/10.5281/zenodo.6653203Test https://zenodo.org/record/6653204Test |
| حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by/4.0/legalcodeTest |
| رقم الانضمام: | edsbas.1B81E6DB |
| قاعدة البيانات: | BASE |
| DOI: | 10.5281/zenodo.6653204 |
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