دورية أكاديمية

Outcomes of high-complexity renal tumours with a Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score of �돟10 after robot-assisted partial nephrectomy with a median 46.5-month follow-up: a tertiary centre experience

التفاصيل البيبلوغرافية
العنوان: Outcomes of high-complexity renal tumours with a Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score of �돟10 after robot-assisted partial nephrectomy with a median 46.5-month follow-up: a tertiary centre experience
المساهمون: College of Medicine, Dept. of Urology, Ali Abdel Raheem, Atalla Alatawi, Dae K. Kim, Abulhasan Sheikh, Ibrahim Alabdulaali, Woong K. Han, Young D. Choi, Koon H. Rha, Rha, Koon Ho, Raheem, Ali Abdel, Choi, Young Deuk, Han, Woong Kyu
بيانات النشر: Blackwell Science
England
سنة النشر: 2016
الوصف: OBJECTIVES: To compare perioperative trifecta achievement and long-term oncological and functional outcomes between patients with renal tumours of low [Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score 6-7], intermediate (PADUA score 8-9) and high (PADUA score �돟10) complexity undergoing robot-assisted partial nephrectomy (RAPN), and to determine predictors for trifecta achievement. PATIENTS AND METHODS: Data were retrospectively analysed from 295 patients, who underwent RAPN, between 2006 and 2015, at a high-volume tertiary centre. Trifecta achievement was the primary outcome measurement. The perioperative parameters and long-term oncological and functional outcomes were the secondary outcome measures. Groups were compared using the Kruskal-Wallis H test or chi-square test. Univariable and multivariable binary logistic regression analyses were used to determine the most important determinant variables associated with trifecta accomplishment. The Kaplan-Meier method was used to estimate overall survival (OS), cancer-specific survival (CSS) and cancer-free survival (CFS). RESULTS: Of the 295 patients, 121 (41%) had a PADUA score of �돟10. Patients in the high-complexity PADUA group had larger tumours (P �돞 0.001), higher clinical stages �돟T1b (P < 0.001), an increased risk of malignancy (P = 0.02), longer warm ischaemia time (P = 0.0030), and higher estimated blood loss (P = 0.001) compared with those in the intermediate- and low-complexity groups. Seven of eight patients who were converted to radical nephrectomy had high-complexity tumours (P = 0.02). Trifecta achievement was less in the high-complexity PADUA group (P < 0.001). Renal functional outcomes did not differ among the groups at follow-up (P > 0.05). There were no significant differences between the groups for OS (P = 0.314), CSS (P = 0.228) and CFS (P = 0.532). In multivariable analysis, the American Society of Anesthesiologists classification, operative time and tumour size were independent predictors of trifecta ...
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
تدمد: 1464-4096
1464-410X
العلاقة: BJU INTERNATIONAL; J00340; 1999~; OAK-2016-08584; https://ir.ymlib.yonsei.ac.kr/handle/22282913/153096Test; T201606097; BJU INTERNATIONAL, Vol.118(5) : 770-778, 2016
DOI: 10.1111/bju.13501
DOI: 10.1111/bju.13501/abstract
الإتاحة: https://doi.org/10.1111/bju.13501Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/153096Test
حقوق: CC BY-NC-ND 2.0 KR ; https://creativecommons.org/licenses/by-nc-nd/2.0/krTest/
رقم الانضمام: edsbas.1A6113CA
قاعدة البيانات: BASE
الوصف
تدمد:14644096
1464410X
DOI:10.1111/bju.13501