دورية أكاديمية
Lean mass and peak bone mineral density.
| العنوان: | Lean mass and peak bone mineral density. |
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| المؤلفون: | Nguyen, HG, Pham, MT, Ho-Pham, LT, Nguyen, TV |
| بيانات النشر: | Elsevier BV |
| سنة النشر: | 2021 |
| المجموعة: | University of Technology Sydney: OPUS - Open Publications of UTS Scholars |
| الوصف: | Objectives The association between body composition parameters and peak bone mineral density is not well documented. The aim of this study is to assess the relative contributions of lean mass and fat mass on peak bone mineral density (BMD). Methods The study involved 416 women and 334 men aged between 20 and 30 years who were participants in the population-based Vietnam Osteoporosis Study. Whole body composition parameters (eg, fat mass and lean mass) and BMD at the lumbar spine and femoral neck were measured by dual-energy X-ray absorptiometry. The association between lean mass and fat mass and BMD was analyzed by the linear regression model using the Least Absolute Shrinkage and Selection Operator (LASSO). Results Peak BMD in men was higher than women, and the difference was more pronounced at the femoral neck (average difference: 0.123 g/cm 2 ; 95% confidence interval [CI] 0.105-0.141 g/cm 2 ) than at the lumbar spine (average difference 0.019 g/cm 2 ; 95% CI, 0.005-0.036 g/cm 2 ). Results of LASSO regression indicated that lean mass was the only predictor of BMD for either men or women. Each kilogram increase in lean mass was associated with ∼0.01 g/cm 2 increase in BMD. Lean mass alone explained 16% and 36% of variation in lumbar spine and femoral neck BMD, respectively. Conclusions Lean mass, not fat mass, is the main determinant of peak bone mineral density. This finding implies that good physical activity during adulthood can contribute to the maximization of peak bone mass during adulthood. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | Print-Electronic; application/pdf |
| اللغة: | English |
| تدمد: | 2405-5255 2405-5263 |
| العلاقة: | Osteoporosis and sarcopenia; Osteoporosis and sarcopenia, 2020, 6, (4), pp. 212-216; http://hdl.handle.net/10453/146470Test |
| الإتاحة: | http://hdl.handle.net/10453/146470Test |
| حقوق: | Elsevier required licence: © 2020 . This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0Test/. The definitive publisher version is available online at https://doi.org/10.1016/j.afos.2020.10.001Test ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.187AD4AD |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 24055255 24055263 |
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