دورية أكاديمية
Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEET beverages trial
| العنوان: | Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEET beverages trial |
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| المؤلفون: | Almiron-Roig, Eva, Navas-Carretero, Santiago, Castelnuovo, Gabriele, Kjølbæk, Louise, Romo, Ana, Normand, Mie, Maloney, Niamh, Hardman, Charlotte A, Hodgkins, Charo E, Moshoyiannis, Hariklia, Finlayson, Graham, Scott, Corey, Raats, Monique M, Harrold, Joanne A, Raben, Anne, Halford, Jason C G, Martínez, J Alfredo |
| المصدر: | Almiron-Roig , E , Navas-Carretero , S , Castelnuovo , G , Kjølbæk , L , Romo , A , Normand , M , Maloney , N , Hardman , C A , Hodgkins , C E , Moshoyiannis , H , Finlayson , G , Scott , C , Raats , M M , Harrold , J A , Raben , A , Halford , J C G & Martínez , J A 2023 , ' Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results .... |
| سنة النشر: | 2023 |
| المجموعة: | University of Copenhagen: Research / Forskning ved Københavns Universitet |
| مصطلحات موضوعية: | /dk/atira/pure/core/keywords/TheFacultyOfScience, Faculty of Science, Insulin, Sweetness enhancers, Glycaemic response, Satiety, Lipids |
| الوصف: | Project SWEET examined the barriers and facilitators to the use of non-nutritive sweeteners and sweetness enhancers (hereafter "S&SE") alongside potential risks/benefits for health and sustainability. The Beverages trial was a double-blind multi-centre, randomised crossover trial within SWEET evaluating the acute impact of three S&SE blends (plant-based and alternatives) vs. a sucrose control on glycaemic response, food intake, appetite sensations and safety after a carbohydrate-rich breakfast meal. The blends were: mogroside V and stevia RebM; stevia RebA and thaumatin; and sucralose and acesulfame-potassium (ace-K). At each 4 h visit, 60 healthy volunteers (53% male; all with overweight/obesity) consumed a 330 mL beverage with either an S&SE blend (0 kJ) or 8% sucrose (26 g, 442 kJ), shortly followed by a standardised breakfast (∼2600 or 1800 kJ with 77 or 51 g carbohydrates, depending on sex). All blends reduced the 2-h incremental area-under-the-curve (iAUC) for blood insulin (p < 0.001 in mixed-effects models), while the stevia RebA and sucralose blends reduced the glucose iAUC (p < 0.05) compared with sucrose. Post-prandial levels of triglycerides plus hepatic transaminases did not differ across conditions (p > 0.05 for all). Compared with sucrose, there was a 3% increase in LDL-cholesterol after stevia RebA-thaumatin (p < 0.001 in adjusted models); and a 2% decrease in HDL-cholesterol after sucralose-ace-K (p < 0.01). There was an impact of blend on fullness and desire to eat ratings (both p < 0.05) and sucralose-acesulfame K induced higher prospective intake vs sucrose (p < 0.001 in adjusted models), but changes were of a small magnitude and did not translate into energy intake differences over the next 24h. Gastro-intestinal symptoms for all beverages were mostly mild. In general, responses to a carbohydrate-rich meal following consumption of S&SE blends with stevia or sucralose were similar to sucrose. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1016/j.appet.2023.106515 |
| الإتاحة: | https://doi.org/10.1016/j.appet.2023.106515Test https://curis.ku.dk/portal/da/publications/impact-of-acute-consumption-of-beverages-containing-plantbased-or-alternative-sweetener-blends-on-postprandial-appetite-food-intake-metabolism-and-gastrointestinal-symptoms-results-of-the-sweet-beverages-trialTest(fd82f554-75f1-4e09-a438-f87505b47b0c).html https://curis.ku.dk/ws/files/337400001/Almiron_Roig_et_al_Appetite_2023_106515_Accepted_manuscript_.pdfTest https://curis.ku.dk/ws/files/338299316/Almiron_Roig_et_al_Appetite_2023_Vol_184_e106515.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.164712A4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.appet.2023.106515 |
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