دورية أكاديمية
Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial.
| العنوان: | Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial. |
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| المؤلفون: | Pavel, Marianne, Gross, David J, Benavent, Marta, Perros, Petros, Srirajaskanthan, Raj, Warner, Richard R P, Kulke, Matthew H, Anthony, Lowell B, Kunz, Pamela L, Hörsch, Dieter, Weickert, Martin O, Lapuerta, Pablo, Jiang, Wenjun, Kassler-Taub, Kenneth, Wason, Suman, Fleming, Rosanna, Fleming, Douglas, Garcia-Carbonero, Rocio |
| سنة النشر: | 2018 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | 5-HIAA, carcinoid syndrome, metastatic neuroendocrine tumor, serotonin, somatostatin analog, Adult, Aged, 80 and over, Diarrhea, Double-Blind Method, Female, Humans, Hydroxyindoleacetic Acid, Male, Malignant Carcinoid Syndrome, Middle Aged, Phenylalanine, Pyrimidines, Somatostatin, Treatment Outcome |
| الوصف: | Telotristat ethyl, a tryptophan hydroxylase inhibitor, was efficacious and well tolerated in the phase 3 TELESTAR study in patients with carcinoid syndrome (CS) experiencing ≥4 bowel movements per day (BMs/day) while on somatostatin analogs (SSAs). TELECAST, a phase 3 companion study, assessed the safety and efficacy of telotristat ethyl in patients with CS (diarrhea, flushing, abdominal pain, nausea or elevated urinary 5-hydroxyindoleacetic acid (u5-HIAA)) with |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1479-6821 |
| العلاقة: | http://hdl.handle.net/10668/12005Test; PMC5811631; https://erc.bioscientifica.com/downloadpdf/journals/erc/25/3/ERC-17-0455.pdfTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811631/pdfTest |
| DOI: | 10.1530/ERC-17-0455 |
| الإتاحة: | https://doi.org/10.1530/ERC-17-0455Test http://hdl.handle.net/10668/12005Test https://erc.bioscientifica.com/downloadpdf/journals/erc/25/3/ERC-17-0455.pdfTest https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811631/pdfTest |
| حقوق: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0Test/ ; open access |
| رقم الانضمام: | edsbas.160CE236 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14796821 |
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| DOI: | 10.1530/ERC-17-0455 |