Exploring the impact of co-exposure timing on drug-drug interactions in signal detection through spontaneous reporting system databases: a scoping review ...

التفاصيل البيبلوغرافية
العنوان: Exploring the impact of co-exposure timing on drug-drug interactions in signal detection through spontaneous reporting system databases: a scoping review ...
المؤلفون: Cocco, Marianna, Carnovale, Carla, Clementi, Emilio, Barbieri, Maria Antonietta, Battini, Vera, Sessa, Maurizio
بيانات النشر: Taylor & Francis
سنة النشر: 2024
المجموعة: DataCite Metadata Store (German National Library of Science and Technology)
مصطلحات موضوعية: Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Information Systems not elsewhere classified, Infectious Diseases, FOS Health sciences
الوصف: Drug-drug interactions (DDIs) are defined as the pharmacological effects produced by the concomitant administration of two or more drugs. To minimize false positive signals and ensure their validity when analyzing Spontaneous Reporting System (SRS) databases, it has been suggested to incorporate key pharmacological principles, such as temporal plausibility. The scoping review of the literature was completed using MEDLINE from inception to March 2023. Included studies had to provide detailed methods for identifying DDIs in SRS databases. Any methodological approach and adverse event were accepted. Descriptive analyzes were excluded as we focused on automatic signal detection methods. The result is an overview of all the available methods for DDI signal detection in SRS databases, with a specific focus on the evaluation of the co-exposure time of the interacting drugs. It is worth noting that only a limited number of studies ( n = 3) have attempted to address the issue of overlapping drug administration times. ...
نوع الوثيقة: dataset
اللغة: unknown
العلاقة: https://dx.doi.org/10.1080/17512433.2024.2343875Test
DOI: 10.6084/m9.figshare.25635665
الإتاحة: https://doi.org/10.6084/m9.figshare.2563566510.1080/17512433.2024.2343875Test
https://tandf.figshare.com/articles/dataset/Exploring_the_impact_of_co-exposure_timing_on_drug-drug_interactions_in_signal_detection_through_spontaneous_reporting_system_databases_a_scoping_review/25635665Test
حقوق: Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcodeTest ; cc-by-4.0
رقم الانضمام: edsbas.151DA973
قاعدة البيانات: BASE