دورية أكاديمية
HOXB7: An Oncogenic Gene in Breast Cancer Cells?
| العنوان: | HOXB7: An Oncogenic Gene in Breast Cancer Cells? |
|---|---|
| المؤلفون: | Rubin, Ethel, Sukumar, Saraswati |
| المساهمون: | JOHNS HOPKINS UNIV BALTIMORE MD SCHOOLOF MEDICINE |
| المصدر: | DTIC AND NTIS |
| سنة النشر: | 2003 |
| المجموعة: | Defense Technical Information Center: DTIC Technical Reports database |
| مصطلحات موضوعية: | Genetic Engineering and Molecular Biology, Medicine and Medical Research, BREAST CANCER, TISSUES(BIOLOGY), DEOXYRIBONUCLEIC ACIDS, CHROMOSOMES, GENES, CELLS(BIOLOGY), MASS SPECTROMETRY, GENOME, ONCOGENESIS, HOMEOBOX GENES, HOXB7 |
| الوصف: | Homeobox genes control anterioposterior body axis patterning during development. Although expressed primarily in developing embryos, a growing body of evidence shows that homeobox gene re-expression in adult tissues is associated with tumorigenesis. Earlier work has shown that introduction of HOXB7, one of the members of this gene family, into non-expressing breast cancer cells induced expression of a number of pro-angiogenic factors and formed tumors upon xenograft into nude mice. We had earlier identified HOXB7 as an overexpressed gene in a SAGE analysis of breast cancer cell lines and wanted to investigate its oncogenic potential in this study. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://www.dtic.mil/docs/citations/ADA417673Test |
| الإتاحة: | http://www.dtic.mil/docs/citations/ADA417673Test http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA417673Test |
| حقوق: | APPROVED FOR PUBLIC RELEASE |
| رقم الانضمام: | edsbas.14E5B83 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |