دورية أكاديمية
Clinical features of type 1 diabetes in older adults and the impact of intermittently scanned continuous glucose monitoring: An Association of British Clinical Diabetologists (ABCD) study
| العنوان: | Clinical features of type 1 diabetes in older adults and the impact of intermittently scanned continuous glucose monitoring: An Association of British Clinical Diabetologists (ABCD) study |
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| المؤلفون: | Deshmukh, H., Adeleke, K., Wilmot, E. G., Folwell, A., Barnes, D., Walker, N., Saunders, S., Ssemmondo, E., Walton, C., Patmore, J., Ryder, R. E. J., Sathyapalan, T. |
| بيانات النشر: | Wiley |
| سنة النشر: | 2024 |
| المجموعة: | RD&E Research Repository (Royal Devon and Exeter NHS Foundation Trust) |
| مصطلحات موضوعية: | Humans, Aged, Diabetes Mellitus, Type 1/drug therapy/epidemiology, Blood Glucose, Glycated Hemoglobin, Blood Glucose Self-Monitoring, Continuous Glucose Monitoring, State Medicine, Hypoglycemia/chemically nduced/epidemiology/prevention & control, Insulins, Hypoglycemic Agents/therapeutic use, continuous glucose monitoring (CGM), glycaemic control, real-world evidence, type 1 diabetes |
| الوصف: | AIMS: To evaluate the clinical features and impact of flash glucose monitoring in older adults with type 1 diabetes (T1D) across age groups defined as young-old, middle-old, and old-old. MATERIALS AND METHODS: Clinicians were invited to submit anonymized intermittently scanned continuous glucose monitoring (isCGM) user data to a secure web-based tool within the National Health Service secure network. We collected baseline data before isCGM initiation, such as demographics, glycated haemoglobin (HbA1c) values from the previous 12 months, Gold scores and Diabetes Distress Scale (DDS2) scores. For analysis, people with diabetes were classified as young-old (65-75 years), middle-old (>75-85 years) and old-old (>85 years). We compared baseline clinical characteristics across the age categories using a t test. All the analyses were performed in R 4.1.2. RESULTS: The study involved 1171 people with diabetes in the young-old group, 374 in the middle-old group, and 47 in the old-old group. There were no significant differences in baseline HbA1c and DDS2 scores among the young-old, middle-old, and old-old age groups. However, Gold score increased with age (3.20 [±1.91] in the young-old vs. 3.46 [±1.94] in the middle-old vs. 4.05 [±2.28] in the old-old group; p < 0.0001). This study showed reduced uptake of insulin pumps (p = 0.005) and structured education (Dose Adjustment For Normal Eating [DAFNE] course; p = 0.007) in the middle-old and old-old populations compared to the young-old population with T1D. With median isCGM use of 7 months, there was a significant improvement in HbA1c in the young-old (p < 0.001) and old-old groups, but not in the middle-old group. Diabetes-related distress score (measured by the DDS2) improved in all three age groups (p < 0.001) and Gold score improved (p < 0.001) in the young-old and old-old populations but not in the middle-old population. There was also a significant improvement in resource utilization across the three age categories following the use of is CGM. ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://linkinghub.elsevier.com/retrieve/pii/S2352-4642Test(23)00340-1; Deshmukh H, Adeleke K, Wilmot EG, Folwell A, Barnes D, Walker N, et al. Clinical features of type 1 diabetes in older adults and the impact of intermittently scanned continuous glucose monitoring: An Association of British Clinical Diabetologists (ABCD) study. Diabetes Obes Metab. 2024;26(4):1333-9.; Diabetes, obesity & metabolism; https://hdl.handle.net/11287/623190Test |
| DOI: | 10.1111/dom.15434 |
| الإتاحة: | https://doi.org/10.1111/dom.15434Test https://hdl.handle.net/11287/623190Test |
| حقوق: | © 2024 John Wiley & Sons Ltd. |
| رقم الانضمام: | edsbas.13E49372 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/dom.15434 |
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