التفاصيل البيبلوغرافية
العنوان: |
Deconstructing Syndemics: The Many Layers of Clustering Multi-Comorbidities in People Living with HIV |
المؤلفون: |
Emmanuel Peprah, Elisabet Caler, Anya Snyder, Fassil Ketema |
المصدر: |
International Journal of Environmental Research and Public Health; Volume 17; Issue 13; Pages: 4704 |
بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
سنة النشر: |
2020 |
المجموعة: |
MDPI Open Access Publishing |
مصطلحات موضوعية: |
HIV, Syndemics, non-communicable diseases, public health, communicable diseases, cardiovascular disease, lung diseases, low and middle-income countries, sleep disorder, health disparity, comorbidity |
جغرافية الموضوع: |
agris |
الوصف: |
The HIV epidemic has dramatically changed over the past 30 years; there are now fewer newly infected people (especially children), fewer AIDS-related deaths, and more people with HIV (PWH) receiving treatment. However, the HIV epidemic is far from over. Despite the tremendous advances in anti-retroviral therapies (ART) and the implementation of ART regimens, HIV incidence (number of new infections over a defined period of time) and prevalence (the burden of HIV infection) in certain regions of the world and socio-economic groups are still on the rise. HIV continues to disproportionally affect highly marginalized populations that constitute higher-risk and stigmatized groups, underserved and/or neglected populations. In addition, it is not uncommon for PWH to suffer enhanced debilitating conditions resulting from the synergistic interactions of both communicable diseases (CDs) and non-communicable diseases (NCDs). While research utilizing only a comorbidities framework has advanced our understanding of the biological settings of the co-occurring conditions from a molecular and mechanistic view, harmful interactions between comorbidities are often overlooked, particularly under adverse socio-economical and behavioral circumstances, likely prompting disease clustering in PWH. Synergistic epidemics (syndemics) research aims to capture these understudied interactions: the mainly non-biological aspects that are central to interpret disease clustering in the comorbidities/multi-morbidities only framework. Connecting population-level clustering of social and health problems through syndemic interventions has proved to be a critical knowledge gap that will need to be addressed in order to improve prevention and care strategies and bring us a step closer to ending the HIV epidemic. |
نوع الوثيقة: |
text |
وصف الملف: |
application/pdf |
اللغة: |
English |
العلاقة: |
Health Economics; https://dx.doi.org/10.3390/ijerph17134704Test |
DOI: |
10.3390/ijerph17134704 |
الإتاحة: |
https://doi.org/10.3390/ijerph17134704Test |
حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
رقم الانضمام: |
edsbas.13BEDF7B |
قاعدة البيانات: |
BASE |