دورية أكاديمية

Inexpensive Synthesis of Poly(Ethylenedioxythiophene‐Sulfobetaine) Films with High Bio‐Antifouling Ability

التفاصيل البيبلوغرافية
العنوان: Inexpensive Synthesis of Poly(Ethylenedioxythiophene‐Sulfobetaine) Films with High Bio‐Antifouling Ability
المؤلفون: Shen, Mo‐Yuan, Huang, Tzu‐Yang, Luo, Chun‐Hao, Huang, Yu‐Chun, Tsai, Yu‐Han, Wang, Tian‐Lin, Yu, Hsiao‐hua
المساهمون: Academia Sinica, Ministry of Science and Technology, Taiwan
المصدر: Journal of the Chinese Chemical Society ; volume 65, issue 1, page 149-155 ; ISSN 0009-4536 2192-6549
بيانات النشر: Wiley
سنة النشر: 2018
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: To prevent nonspecific interactions with biomolecules (e.g., proteins), blood cells, and microorganisms (e.g., bacteria, viruses, fungi, parasites) that can exert severe side effects, several bio‐inspired antifouling materials, including poly(ethylene glycol) and zwitterionic phosphocholine, sulfobetaine (SB), and carboxybetaine derivatives have been applied in biomedical electronic devices. In this paper, we report the development of an economical strategy for synthesizing ethylenedioxythiophene (EDOT)‐SB and creating the corresponding highly antifouling polymer films though electrochemical polymerization. The poly(EDOT‐SB) films inhibited 95% of the nonspecific binding of proteins from serum and prevented the adhesion of fibroblast cells. Moreover, the antifouling properties of the conducting film were maintained in both the oxidized and reduced states of PEDOT. Such zwitterionic, functionalized conducting polymer films appear to have great potential for application to bio‐electronic implant devices.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1002/jccs.201700437
الإتاحة: https://doi.org/10.1002/jccs.201700437Test
حقوق: http://onlinelibrary.wiley.com/termsAndConditions#vorTest
رقم الانضمام: edsbas.13B41FC3
قاعدة البيانات: BASE