التفاصيل البيبلوغرافية
| العنوان: |
Intraarterial LepA injection via ipsilateral ICA reduced pSTAT3 and pSmad2 levels in the CA1 region following ischemia and reperfusion. |
| المؤلفون: |
Amit Benbenishty (6524375), Jacob Schneiderman (5851292) |
| سنة النشر: |
2022 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Immunology, Developmental Biology, Cancer, Infectious Diseases, injured brain area, lesions derive expression, leptin therapy may, dose leptin antagonist, +inhibition%22">xlink "> inhibition, saline solution via, injected mice completed, hippocampal ca1 region, blocking leptin activity, also involves processes, leptin antagonist treatment, reperfusion , reperfusion reduced apoptosis, leptin antagonist, %22">xlink ">, leptin activity, ca1 region, treatment reduced, local expression |
| الوصف: |
( A ) Representative images of pSTAT3 signal indicating its presents in IR/saline-injected (brown), but not in IR/LepA-treated mice. ( B ) Representative images of pSmad2 signal demonstrated that all viable pyramidal cells in both treatment groups were pSmad2 positive, while in the surrounding of the CA1 region pSmad2 was higher in IR/saline-injected mice compared to IR/LepA-injected counterparts. Scale bars are 500 μm and 100 μm for low and high magnification, respectively. ( C ) Less pSmad2-positive cells were found surrounding the CA1 region in IR/saline compared to IR/LepA treated mice (n = 4, unpaired two-tailed Student t-test, t (6) = 5.058, p = 0 . 0023 ). |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/figure/Intraarterial_LepA_injection_via_ipsilateral_ICA_reduced_pSTAT3_and_pSmad2_levels_in_the_CA1_region_following_ischemia_and_reperfusion_/18175432Test |
| DOI: |
10.1371/journal.pone.0261644.g004 |
| الإتاحة: |
https://doi.org/10.1371/journal.pone.0261644.g004Test |
| حقوق: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.1377A995 |
| قاعدة البيانات: |
BASE |
