دورية أكاديمية

One-year outcome of critically ill patients with systemic rheumatic disease: a multicenter cohort study

التفاصيل البيبلوغرافية
العنوان: One-year outcome of critically ill patients with systemic rheumatic disease: a multicenter cohort study
المؤلفون: Larcher, R., Pineton de Chambrun, Marc, Garnier, Fanny, Rubenstein, Emma, Carr, Julie, Charbit, Jonathan, Chalard, Kevin, Mourad, Marc, Amalric, Matthieu, Platon, Laura, Brunot, Vincent, Amoura, Zahir, Jaber, Samir, Jung, Boris, Luyt, Charles-Edouard, Klouche, Kada
المساهمون: Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Physiologie & médecine expérimentale du Cœur et des Muscles U 1046 (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de cardiologie CHU Pitié-Salpêtrière, CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition CHU Pitié Salpêtrière (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière AP-HP
المصدر: ISSN: 0012-3692.
بيانات النشر: HAL CCSD
American College of Chest Physicians
سنة النشر: 2020
المجموعة: Université de Montpellier: HAL
مصطلحات موضوعية: corticosteroids, intensive care, outcomes, prognostic factors, systemic rheumatic diseases, [SDV]Life Sciences [q-bio]
الوصف: International audience ; Background: Critically ill patients with systemic rheumatic disease (SRD) have benefited from better provision of rheumatic and critical care in recent years. Recent comprehensive data regarding in-hospital mortality rates and, most importantly, long-term outcomes are scarce.Research question: The aim of this study was to assess short and long-term outcome of patients with SRD who were admitted to the ICU.Study design and methods: All records of patients with SRD who were admitted to ICU between 2006 and 2016 were reviewed. In-hospital and one-year mortality rates were assessed, and predictive factors of death were identified.Results: A total of 525 patients with SRD were included. Causes of admission were most frequently shock (40.8%) and acute respiratory failure (31.8%). Main diagnoses were infection (39%) and SRD flare-up (35%). In-hospital and one-year mortality rates were 30.5% and 37.7%, respectively. Predictive factors that were associated with in-hospital and one-year mortalities were, respectively, age, prior corticosteroid therapy, simplified acute physiology score II ≥50, need for invasive mechanical ventilation, or need for renal replacement therapy. Knaus scale C or D and prior conventional disease modifying antirheumatic drug therapy was associated independently with death one-year after ICU admission.Interpretation: Critically ill patients with SRD had a fair outcome after an ICU stay. Increased age, prior corticosteroid therapy, and severity of critical illness were associated significantly with short- and long-term mortality rates. The one-year mortality rate was also associated with prior health status and conventional disease modifying antirheumatic drug therapy.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32289313; hal-02543275; https://hal.science/hal-02543275Test; https://hal.science/hal-02543275/documentTest; https://hal.science/hal-02543275/file/2020%20Larcher%20et%20al.,%20One%20year.pdfTest; PUBMED: 32289313
DOI: 10.1016/j.chest.2020.03.050
الإتاحة: https://doi.org/10.1016/j.chest.2020.03.050Test
https://hal.science/hal-02543275Test
https://hal.science/hal-02543275/documentTest
https://hal.science/hal-02543275/file/2020%20Larcher%20et%20al.,%20One%20year.pdfTest
حقوق: info:eu-repo/semantics/OpenAccess
رقم الانضمام: edsbas.103B85DA
قاعدة البيانات: BASE
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