التفاصيل البيبلوغرافية
| العنوان: |
The Benefits of Water from Nitrodi’s Spring: The In Vitro Studies Leading the Potential Clinical Applications |
| المؤلفون: |
Ilaria Mormile, Fabiana Tuccillo, Francesca Della Casa, Valentina D’Aiuto, Nunzia Montuori, Marina De Rosa, Filomena Napolitano, Amato de Paulis, Francesca Wanda Rossi |
| المصدر: |
International Journal of Molecular Sciences ; Volume 24 ; Issue 18 ; Pages: 13685 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2023 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Nitrodi, spring, thermalism, wound healing, balneotherapy, water, Romans, spa |
| جغرافية الموضوع: |
agris |
| الوصف: |
Natural products (water, plants, and minerals) have been studied for diverse applications in health and disease. Since there has been a growing interest in the introduction of thermal water as a clinical complementary approach in the treatment of low-grade inflammation and stress-related conditions, this review focuses on the oldest spa in the world: Nitrodi’s spring. Substantial studies in the 1960s showed that both the internal and external use of Nitrodi’s water yielded several benefits in physiological processes and in treating certain disorders, mainly allergic and autoimmune inflammatory conditions. More recently, a novel interest in Nitrodi’s water has prompted researchers to further explore the effects of this water and shed light on the molecular mechanisms sustaining its therapeutic efficacy. In different epithelial cell models, Nitrodi’s water had strong promotional effects on proliferation, cell migration, cell viability, and fibroblast to myofibroblast transition, all of which essential for wound healing and tissue remodeling. Moreover, Nitrodi’s water exhibited anti-oxidant and anti-inflammatory properties through the inhibition of ROS production and protein S-nitrosylation. Here, we have collected the clinical and basic data on Nitrodi’s water and reviewed articles that have discussed its use as a potential treatment for several inflammatory and autoimmune diseases and age-related skin deterioration. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms241813685Test |
| DOI: |
10.3390/ijms241813685 |
| الإتاحة: |
https://doi.org/10.3390/ijms241813685Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.102C3AB2 |
| قاعدة البيانات: |
BASE |
