Testing similarity of parametric competing risks models for identifying potentially similar pathways in healthcare

التفاصيل البيبلوغرافية
العنوان: Testing similarity of parametric competing risks models for identifying potentially similar pathways in healthcare
المؤلفون: Möllenhoff, Kathrin, Binder, Nadine, Dette, Holger
سنة النشر: 2024
المجموعة: Statistics
مصطلحات موضوعية: Statistics - Methodology, Statistics - Applications
الوصف: The identification of similar patient pathways is a crucial task in healthcare analytics. A flexible tool to address this issue are parametric competing risks models, where transition intensities may be specified by a variety of parametric distributions, thus in particular being possibly time-dependent. We assess the similarity between two such models by examining the transitions between different health states. This research introduces a method to measure the maximum differences in transition intensities over time, leading to the development of a test procedure for assessing similarity. We propose a parametric bootstrap approach for this purpose and provide a proof to confirm the validity of this procedure. The performance of our proposed method is evaluated through a simulation study, considering a range of sample sizes, differing amounts of censoring, and various thresholds for similarity. Finally, we demonstrate the practical application of our approach with a case study from urological clinical routine practice, which inspired this research.
Comment: 21 pages, 6 figures
نوع الوثيقة: Working Paper
الوصول الحر: http://arxiv.org/abs/2401.04490Test
رقم الانضمام: edsarx.2401.04490
قاعدة البيانات: arXiv