تقرير
Quadruplex detection in human cells
| العنوان: | Quadruplex detection in human cells |
|---|---|
| المؤلفون: | Monchaud, David |
| سنة النشر: | 2019 |
| المجموعة: | Quantitative Biology |
| مصطلحات موضوعية: | Quantitative Biology - Biomolecules, Quantitative Biology - Subcellular Processes |
| الوصف: | DNA and RNA quadruplexes are extensively studied for the key roles they are suspected to play in the cellular regulation networks at both genomic and transcriptomic levels. The reliable detection of quadruplexes in cells was and remains a challenging task. Here, we describe the various strategies that have been implemented over the past years to visualize functionally relevant DNA and RNA quadruplexes in human cells, from immunodetection studies to the design and use of quadruplex-specific turn-on fluorescent probes. Comment: Review, 28 pages, 10 figures, 135 references |
| نوع الوثيقة: | Working Paper |
| الوصول الحر: | http://arxiv.org/abs/1910.07023Test |
| رقم الانضمام: | edsarx.1910.07023 |
| قاعدة البيانات: | arXiv |
| الوصف غير متاح. |