EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
| العنوان: | EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data |
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| المؤلفون: | Bock, Christoph, Halachev, Konstantin, Büch, Joachim, Lengauer, Thomas |
| المصدر: | Genome Biology Genome Biology; Vol 10 |
| بيانات النشر: | BioMed Central, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | User-Computer Interface, ComputingMethodologies_PATTERNRECOGNITION, Vertebrates, Animals, Computational Biology, ComputingMethodologies_GENERAL, Genomics, Databases, Nucleic Acid, Software, Epigenesis, Genetic |
| الوصف: | EpiGRAPH is a genome-scale data-mining software tool that enables users to identify epigenetic and gene regulatory features in large datasets of genomic regions. The EpiGRAPH web service enables biologists to uncover hidden associations in vertebrate genome and epigenome datasets. Users can upload sets of genomic regions and EpiGRAPH will test multiple attributes (including DNA sequence, chromatin structure, epigenetic modifications and evolutionary conservation) for enrichment or depletion among these regions. Furthermore, EpiGRAPH learns to predictively identify similar genomic regions. This paper demonstrates EpiGRAPH's practical utility in a case study on monoallelic gene expression and describes its novel approach to reproducible bioinformatic analysis. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1465-6914 1465-6906 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a5eb9f990fdc4f322894c9e53565c538Test http://europepmc.org/articles/PMC2688269Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....a5eb9f990fdc4f322894c9e53565c538 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14656914 14656906 |
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