التفاصيل البيبلوغرافية
العنوان: |
Discovery and optimization of a novel CNS penetrant series of mGlu |
المؤلفون: |
Caitlin N, Kent, Mark G, Fulton, Kaylee J, Stillwell, Jonathan W, Dickerson, Matthew T, Loch, Alice L, Rodriguez, Anna L, Blobaum, Olivier, Boutaud, Jerri L, Rook, Colleen M, Niswender, P Jeffrey, Conn, Craig W, Lindsley |
المصدر: |
Bioorganicmedicinal chemistry letters. 37 |
سنة النشر: |
2021 |
مصطلحات موضوعية: |
Catalepsy, Disease Models, Animal, Mice, Structure-Activity Relationship, Neuroprotective Agents, Allosteric Regulation, Dose-Response Relationship, Drug, Molecular Structure, Drug Discovery, Animals, Haloperidol, Parkinson Disease, Receptors, Metabotropic Glutamate |
الوصف: |
A high throughput screen (HTS) identified a novel, but weak (EC |
تدمد: |
1464-3405 |
الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=pmid________::aa0e4acb766ebacc10e8996ddcf9fb14Test https://pubmed.ncbi.nlm.nih.gov/33556572Test |
رقم الانضمام: |
edsair.pmid..........aa0e4acb766ebacc10e8996ddcf9fb14 |
قاعدة البيانات: |
OpenAIRE |