Discovery and optimization of a novel CNS penetrant series of mGlu

التفاصيل البيبلوغرافية
العنوان: Discovery and optimization of a novel CNS penetrant series of mGlu
المؤلفون: Caitlin N, Kent, Mark G, Fulton, Kaylee J, Stillwell, Jonathan W, Dickerson, Matthew T, Loch, Alice L, Rodriguez, Anna L, Blobaum, Olivier, Boutaud, Jerri L, Rook, Colleen M, Niswender, P Jeffrey, Conn, Craig W, Lindsley
المصدر: Bioorganicmedicinal chemistry letters. 37
سنة النشر: 2021
مصطلحات موضوعية: Catalepsy, Disease Models, Animal, Mice, Structure-Activity Relationship, Neuroprotective Agents, Allosteric Regulation, Dose-Response Relationship, Drug, Molecular Structure, Drug Discovery, Animals, Haloperidol, Parkinson Disease, Receptors, Metabotropic Glutamate
الوصف: A high throughput screen (HTS) identified a novel, but weak (EC
تدمد: 1464-3405
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::aa0e4acb766ebacc10e8996ddcf9fb14Test
https://pubmed.ncbi.nlm.nih.gov/33556572Test
رقم الانضمام: edsair.pmid..........aa0e4acb766ebacc10e8996ddcf9fb14
قاعدة البيانات: OpenAIRE