Salivary lactate dehydrogenase and aminotransferases in diabetic patients
| العنوان: | Salivary lactate dehydrogenase and aminotransferases in diabetic patients |
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| المؤلفون: | Katarzyna Skoskiewicz-Malinowska, Barbara Malicka, Urszula Kaczmarek |
| المصدر: | Medicine |
| بيانات النشر: | Wolters Kluwer Health, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Saliva, alanine aminotransferases, Alpha (ethology), Diagnostic Accuracy Study, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Statistical significance, Lactate dehydrogenase, Diabetes mellitus, medicine, Humans, saliva, biology, L-Lactate Dehydrogenase, business.industry, Case-control study, lactate dehydrogenase, Alanine Transaminase, 030206 dentistry, General Medicine, Middle Aged, medicine.disease, Endocrinology, Diabetes Mellitus, Type 1, Alanine transaminase, chemistry, Diabetes Mellitus, Type 2, 030220 oncology & carcinogenesis, Case-Control Studies, diabetes mellitus, biology.protein, aspartate aminotransferases, Female, Hemoglobin, business, Research Article |
| الوصف: | Diabetes mellitus (DM) is a group of metabolic diseases resulting from impaired insulin secretion and/or action. DM is characterized by hyperglycemia that can lead to the dysfunction or damage of organs, including the salivary glands. The aim of this study was to compare the levels of salivary lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in diabetic patients. The study was approved by the Bioethics Committee of Wroclaw Medical University (Poland). The study comprised 90 adults of both sexes, aged 21 to 57 years. The patients were divided into 3 groups: type 1 diabetics (D1), type 2 diabetics (D2), and a healthy control group (C). Each group consisted of 30 age- and sex-matched subjects. Total protein (P, by Lowry method), LDH, AST, ALT (with Alpha Diagnostics kits), and salivary flow rate were measured in unstimulated mixed saliva. The level of glycosylated hemoglobin (HbA1c) was measured with DCA 2000 Reagent Kit. The obtained data were analyzed using the Mann–Whitney U test and the Spearman rank at a significance level of P |
| اللغة: | English |
| تدمد: | 1536-5964 0025-7974 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff47be10a4bef7b27b621b7b48d1a791Test http://europepmc.org/articles/PMC5134853Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ff47be10a4bef7b27b621b7b48d1a791 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15365964 00257974 |
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