Capacity adiposity indices to identify metabolic syndrome in subjects with intermediate cardiovascular risk (MARK study)
| العنوان: | Capacity adiposity indices to identify metabolic syndrome in subjects with intermediate cardiovascular risk (MARK study) |
|---|---|
| المؤلفون: | Manuel A. Gómez-Marcos, José I. Recio-Rodríguez, Marta Gomez-Sanchez, Cristina Agudo-Conde, Leticia Gomez-Sanchez, Luis García-Ortiz, Rafel Ramos, Fernando Rigo, Ruth Martí, Maria C. Patino-Alonso, Emiliano Rodriguez-Sanchez, Jose A. Maderuelo-Fernandez |
| المصدر: | PLoS ONE, 2019, vol. 14, núm. 1, p. e0209992 Articles publicats (D-CM) DUGiDocs – Universitat de Girona instname PLoS ONE PLoS ONE, Vol 14, Iss 1, p e0209992 (2019) |
| بيانات النشر: | Public Library of Science, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, Physiology, humanos, Sistema cardiovascular -- Malalties, Blood Pressure, 030204 cardiovascular system & hematology, Biochemistry, Vascular Medicine, Body Mass Index, 0302 clinical medicine, Risk Factors, Medicine and Health Sciences, Public and Occupational Health, mediana edad, Adiposity, Waist-to-height ratio, Metabolic Syndrome, anciano, Multidisciplinary, Confounding, Body Shape Index, Drugs, Middle Aged, Lipids, Antihypertensive Drugs, Cholesterol, Physiological Parameters, Adipose Tissue, Cardiovascular Diseases, Obesity, Abdominal, Medicine, Obesitat, Female, adiposidad, Anatomy, Research Article, medicine.medical_specialty, Science, enfermedades cardiovasculares, 030209 endocrinology & metabolism, 03 medical and health sciences, curva ROC, Internal medicine, medicine, factores de riesgo, Humans, Obesity, obesidad, National Cholesterol Education Program, Glycemic, Aged, Pharmacology, Waist-Height Ratio, business.industry, Cardiovascular system -- Diseases, índice de masa corporal, Body Weight, Biology and Life Sciences, Physical Activity, medicine.disease, Biological Tissue, Cross-Sectional Studies, ROC Curve, Metabolic Disorders, Metabolic syndrome, business, Body mass index, estudios transversales |
| الوصف: | Background Obesity increases mortality, and is linked to cardiovascular diseases and metabolic syndrome (MetS). Therefore, the purpose of this study was to analyze the ability of different adiposity indices to identify subjects with MetS among people with intermediate cariovascular risk. Materials and methods The cross-sectional study involved 2478 subjects, recruited by the MARK study. Adiposity measures: general adiposity by body mass index (BMI), central adiposity by waist-to-height ratio (WHtR), fat mass percent by the Clinica Universidad de Navarra-body adiposity estimator (CUN-BAE), percentage of body fat and of visceral adipose tissue by body roundness index (BRI) and visceral obesity and general adiposity with body shape index (ABSI). The diagnosis of MetS was made in accordance with the criteria established in the international consensus of the Joint Scientific Statement National Cholesterol Education Program III. Results The highest correlation coefficients were obtained by the glycemic components (HbA1c and FPG) of the MetS and ranged from 0.155 to 0.320. The exception was ABSI, which showed lower values in the global analysis and in the males. Values of the area under the ROC curve with the adiposity indices ranged from 0.773 with the BMI in males to 0.567 with ABSI in males. In the logistic regression analysis, all adiposity factors, except ABSI, showed similar OR values of MetS after adjusting for possible confounding factors. In the global analysis, the adiposity index that showed a highest OR of MetS was CUN-BAE (OR 5.50; 95% CI 4.27-7.09). In the analysis by gender, the highest ORs were BMI in males (OR 5.98; 95% CI 4.70-7.60) and both WHtR and BRI in females (OR 4.15; 95% CI 3.09-5.58). Conclusion All adiposity indices, except for ABSI, show an association with MetS and similar ability to detect subjects with MetS among people with intermediate cariovascular risk. This work was supported by grants from the Spanish Ministry of Science and Innovation (MICINN), the Carlos III Health Institute/European Regional Development Fund (ERDF) (MICINN, ISCIII/FEDER) (Red RedIAPP RD06/0018, Research Groups: RD16/0007/0003, RD16/0007/0004, RD16/0007/0008), the Health Research Fund (PI10/01088, PI10/02077, PI10/02043; PI13/01930), and the Regional Health Management of Castile and Leon (GRS 635/A/11; GRS 906/B/14). |
| وصف الملف: | application/pdf |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe770fdf09896b9a1c808dd32593032fTest http://hdl.handle.net/10256/18147Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....fe770fdf09896b9a1c808dd32593032f |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |