Magnetic resonance imaging changes in Asian people living with HIV
| العنوان: | Magnetic resonance imaging changes in Asian people living with HIV |
|---|---|
| المؤلفون: | Shigeru Furui, Hiroshi Oba, Yusuke Yoshino, Takatoshi Kitazawa, Ichiro Koga, Hiroshi Matsuda, Yasuo Ota |
| المصدر: | Infectious Diseases. 53:89-93 |
| بيانات النشر: | Informa UK Limited, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, 0301 basic medicine, Microbiology (medical), Pediatrics, medicine.medical_specialty, 030106 microbiology, Human immunodeficiency virus (HIV), HIV Infections, Younger people, medicine.disease_cause, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, medicine, Humans, 030212 general & internal medicine, General Immunology and Microbiology, medicine.diagnostic_test, business.industry, Leukoaraiosis, Brain, Magnetic resonance imaging, General Medicine, Middle Aged, Magnetic Resonance Imaging, Infectious Diseases, sense organs, Atrophy, business |
| الوصف: | Previous studies have reported a significant increase in age-related magnetic resonance imaging (MRI) changes in relatively younger people living with HIV (PLWH). However, there is little data available for brain changes in Asian PLWH. The data to differentiate HIV specific brain change from usual aging change was also sparse. To clarify them, we assessed the presence of leukoaraiosis and brain atrophic changes on MRI in young and middle-aged Japanese PLWH.We reviewed data from well-controlled PLWH (age: 20-64 years) and coeval controls. We evaluated the presence of leukoaraiosis, as well as the extent of whole-brain grey matter (GM) atrophy and parahippocampal atrophy on brain MRI and determined between-group differences. Moreover, we evaluated the severity of parahippocampal atrophy based on the voxel-based specific regional analysis system for Alzheimer's disease.We enrolled 40 PLWH and 33 controls (median age: 40.15 and 48.00 years, respectively, [Aging changes in the brain were significantly more prevalent in well-controlled Japanese PLWH. However, the process of atrophic brain changes might differ between HIV and one of age-related diseases, Alzheimer's disease. |
| تدمد: | 2374-4243 2374-4235 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc56125754edd7d480f3f97a5510d0e1Test https://doi.org/10.1080/23744235.2020.1825797Test |
| رقم الانضمام: | edsair.doi.dedup.....fc56125754edd7d480f3f97a5510d0e1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23744243 23744235 |
|---|