Carriage of ESBL-producing Enterobacteriaceae in French hospitals: the PORTABLSE study
| العنوان: | Carriage of ESBL-producing Enterobacteriaceae in French hospitals: the PORTABLSE study |
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| المؤلفون: | D. Lecointe, Thomas Guillard, I. Grall, Benoit Pilmis, Jean-Ralph Zahar, Anne Limelette, Assaf Mizrahi, N. Bourgeois Nicolaos, Vincent Cattoir, G. Marcadé, A. Le Monnier, Isabelle Poilane |
| المساهمون: | Centre d'infectiologie Necker-Pasteur [CHU Necker], Institut Pasteur [Paris]-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Pontchaillou [Rennes], Université de Reims Champagne-Ardenne (URCA), Centre hospitalier Saint-Joseph [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP) |
| المصدر: | Journal of Hospital Infection Journal of Hospital Infection, WB Saunders, 2018, 98 (3), pp.247-252. ⟨10.1016/j.jhin.2017.11.022⟩ |
| بيانات النشر: | Elsevier BV, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Microbiology (medical), medicine.medical_specialty, Klebsiella pneumoniae, [SDV]Life Sciences [q-bio], 030106 microbiology, Prevalence, Drug resistance, beta-Lactamases, law.invention, Feces, 03 medical and health sciences, 0302 clinical medicine, Enterobacteriaceae, Risk Factors, law, Internal medicine, Humans, Medicine, 030212 general & internal medicine, Escherichia coli Infections, ComputingMilieux_MISCELLANEOUS, Aged, Aged, 80 and over, Univariate analysis, biology, business.industry, Incidence (epidemiology), Enterobacteriaceae Infections, General Medicine, Middle Aged, biology.organism_classification, Intensive care unit, Hospitals, Klebsiella Infections, 3. Good health, Infectious Diseases, Carriage, Carrier State, Female, France, business |
| الوصف: | Currently, contact precautions are recommended for patients colonized or infected with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE). Recent studies have challenged this strategy. This study aimed to assess the rate of ESBL-PE faecal carriage among hospitalized patients according to type of hospital ward, and to identify risk factors associated with carriage.A point prevalence study was conducted in five different types of hospital ward [medical, surgical, intensive care unit (ICU), after care and rehabilitation, and geriatric] in eight French hospitals. All patients included in the study provided a fresh stool sample.In total, 554 patients were included in the study, with a median age of 73 years (range 60-82 years). The overall faecal carriage rate of ESBL-PE was 17.7%. The most frequently encountered species among ESBL-PE was Escherichia coli (71.4%), followed by Klebsiella pneumoniae (14.3%). Risk factors associated with ESBL-PE faecal carriage on univariate analysis were: living in the Paris region (P0.01) and hospitalization on a geriatric ward (P0.01). Interestingly, the cumulative duration of hospital stay before screening was not associated with a significantly higher prevalence of ESBL-PE carriage, regardless of ward type. The ESBL-PE colonization rate was much higher for patients hospitalized on geriatric wards (28.1%) and ICUs (21.7%) compared with those for patients hospitalized on surgical wards (14.8%), medical wards (12.8%) or aftercare and rehabilitation (11.2%).The overall prevalence of ESBL-PE faecal carriage was 17.7%, with only 21% of patients identified previously as carriers. The delay between admission and screening was not associated with an increase in ESBL-PE faecal carriage. |
| تدمد: | 0195-6701 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd3e0fe5482870f86515a929a0e4b4dTest https://doi.org/10.1016/j.jhin.2017.11.022Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....fbd3e0fe5482870f86515a929a0e4b4d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 01956701 |
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