Reliability of real‐time continuous glucose monitoring in infants
| العنوان: | Reliability of real‐time continuous glucose monitoring in infants |
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| المؤلفون: | Katsuaki Toyoshima, Masahiko Kawai, Tomoyuki Shimokaze, Seiichi Tomotaki |
| المصدر: | Pediatrics International. 61:1001-1006 |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Blood Glucose, Male, medicine.medical_specialty, endocrine system diseases, 030204 cardiovascular system & hematology, Hypoglycemia, Mean difference, 03 medical and health sciences, Low glucose, 0302 clinical medicine, Computer Systems, 030225 pediatrics, Internal medicine, medicine, Humans, Monitoring, Physiologic, business.industry, Continuous glucose monitoring, Neonatal hypoglycemia, Infant, Newborn, Reproducibility of Results, nutritional and metabolic diseases, medicine.disease, Glycemic management, Clinical Alarms, Pediatrics, Perinatology and Child Health, Cardiology, Female, business, Neurological impairment, Biomarkers |
| الوصف: | Background Neonatal hypoglycemia is a common and treatable risk factor for neurological impairment. Real-time continuous glucose monitoring (RT-CGM) can show glucose concentration in real time. Using an RT-CGM alarm, physicians can be alerted and intervene in hypoglycemia. No reports, however, have evaluated the reliability of RT-CGM at low glucose levels in infants. This study therefore investigated the difference between blood glucose (BG) and RT-CGM sensor data at low glucose levels and assessed the optimum method of using a hypoglycemic alarm in infants. Methods We enrolled infants whose glycemic management was difficult. We calculated the mean absolute difference (MAD) and mean absolute relative difference (MARD) between BG and RT-CGM sensor data. We compared the MAD and MARD between the low BG fluctuation and high BG fluctuation groups. Results We used RT-CGM for 12 patients (29 times) and investigated 448 pairs of BG and RT-CGM sensor data. The MAD between these pairs was 9.3 ± 8.9 mg/dL, and the MARD was 11.5%. The MAD at low glucose was 7.7 ± 6.0 mg/dL, and the MARD was 16.2%. The MAD and MARD were 6.8 ± 5.4 mg/dL and 7.8% in the low fluctuation group and 10.1 ± 9.5 mg/dL and 12.7% in the high fluctuation group, respectively. Conclusions The difference between BG and RT-CGM sensor data changes with the degree of fluctuation in BG. When physicians set the hypoglycemic alarm, consideration of this difference and a change in the alarm setting according to the degree of fluctuation in BG may be useful. |
| تدمد: | 1442-200X 1328-8067 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84cc2aa6883b30ceb826bf72d9a35e3Test https://doi.org/10.1111/ped.13961Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....f84cc2aa6883b30ceb826bf72d9a35e3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1442200X 13288067 |
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