Expression of Chemokine CCL28 in Ulcerative Colitis Patients
| العنوان: | Expression of Chemokine CCL28 in Ulcerative Colitis Patients |
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| المؤلفون: | Kook Lae Lee, Dong-Seok Lee, Jiwon Kim, Sue Shin, Su Hwan Kim, Ji Bong Jeong |
| المصدر: | Gut and Liver |
| بيانات النشر: | The Editorial Office of Gut and Liver, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Chemokine, medicine.medical_specialty, Biopsy, Inflammatory bowel disease, Gastroenterology, Serology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Disease activity, Colitis, Alimentary Tract, Hepatology, biology, business.industry, Biomarker, medicine.disease, Ulcerative colitis, CCL28, Chemokines, CC, 030220 oncology & carcinogenesis, biology.protein, Immunohistochemistry, Biomarker (medicine), Original Article, Colitis, Ulcerative, 030211 gastroenterology & hepatology, business, Serologic markers, Biomarkers |
| الوصف: | Background/Aims: Ulcerative colitis (UC) is an inflammatory bowel disease for which new serological markers are required. The purpose of this study was to assess the role of the mucosa-associated epithelial chemokine CCL28 in UC. Methods: The study included 50 patients; of these, 25 were patients with UC, and 25 were healthy controls. The levels of serum CCL28 were analyzed using enzyme-linked immunosorbent assay. CCL28 expression was analyzed by immunohistochemistry (IHC) in 15 representative colon tissues biopsied based on disease activity (UC patients with severe activity, five samples; UC patients with mild activity, five samples; healthy controls, five samples). Results: The serum CCL28 levels were remarkably higher (p |
| تدمد: | 2005-1212 1976-2283 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79e88aff40a93363f8041165b5ec0d9Test https://doi.org/10.5009/gnl19273Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f79e88aff40a93363f8041165b5ec0d9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20051212 19762283 |
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