High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil
| العنوان: | High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
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| المؤلفون: | José Nélio Januário, Marina Lobato Martins, Roberto Vagner Puglia Ladeira, Christiane de Souza Martins, Verônica Guimarães de Souza, Camila Moreira Serra e Silva, Claudyene Pires, Anna Bárbara F. Carneiro-Proietti, Elba Gomide Mochel, Samea Cristina Gomes |
| المصدر: | Revista da Sociedade Brasileira de Medicina Tropical v.45 n.2 2012 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 2, Pp 159-162 (2012) |
| بيانات النشر: | FapUNIFESP (SciELO), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Microbiology (medical), Sexually transmitted disease, lcsh:Arctic medicine. Tropical medicine, Adolescent, lcsh:RC955-962, Cross-sectional study, Blotting, Western, Population, Enzyme-Linked Immunosorbent Assay, Prenatal care, Real-Time Polymerase Chain Reaction, Virus, Young Adult, Pregnancy, Prevalence, medicine, Humans, Prevalência, Human T cell lymphotropic virus type 1, Pregnancy Complications, Infectious, Young adult, education, Human T-lymphotropic virus 1, education.field_of_study, business.industry, Brasil, Human T-lymphotropic virus 2, Infant, Newborn, Maranhão, Middle Aged, medicine.disease, HTLV-I Infections, Cross-Sectional Studies, Infectious Diseases, Socioeconomic Factors, HTLV-1/2, HTLV-II Infections, Gravidez, Female, Parasitology, business, Brazil, Demography |
| الوصف: | INTRODUCTION: Human T cell lymphotropic virus type 1 (HTLV-1) is endemic in the Caribbean, Japan, South America and regions of Africa. HTLV-2 is present in Native American populations and associated with IV drug use in Europe and North America. In Brazil, it is estimated that 1.5 million people are infected with HTLV-1/2. The study objective was to determine HTLV-1/2 prevalence in pregnant women in the prenatal care from three public services in São Luis, State of Maranhão, Brazil, and to counsel seropositive women to reduce viral transmission. METHODS: A cross-sectional study was conducted from February to December 2008; women with age of 18 to 45 years, with low risk for sexually transmitted disease (STD) were invited to participate. Blood samples were collected in filter paper, and HTLV-1/2 immunoenzymatic test (ELISA) was performed as a screening test. Women with reactive results were submitted to peripheral venous blood collection for ELISA repetition, followed by Western blot (WB) and real-time PCR to confirm and discriminate the infection between virus types 1 and 2. RESULTS: Of the 2,044 women tested, seven (0.3%) were ELISA reactive and confirmed positive (four were HTLV-1, and three were HTLV-2). All positive women were oriented not to breastfeed their newborns. CONCLUSIONS: This study showed that the virus is present in high prevalence in that population. Further studies covering other segments of the population are necessary to better characterize the presence of HTLV-1/2 in Maranhão and to elicit measures to prevent its spread. |
| وصف الملف: | text/html |
| تدمد: | 0037-8682 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cd186698bc05c0abc9a962fc8e8cb6Test https://doi.org/10.1590/s0037-86822012000200004Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f6cd186698bc05c0abc9a962fc8e8cb6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00378682 |
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