Rabbit hemorrhagic disease virus type 2 epidemic in a rabbit colony in Japan
| العنوان: | Rabbit hemorrhagic disease virus type 2 epidemic in a rabbit colony in Japan |
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| المؤلفون: | Hiroto Fukui, Yumi Une, Hiroshi Shimoda, Chizuka Henmi, Sho Kadekaru |
| المصدر: | The Journal of Veterinary Medical Science |
| بيانات النشر: | Japanese Society of Veterinary Science, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | rabbit hemorrhagic disease, Hemorrhagic Disease Virus, Rabbit, Disease, Virus, Japan, Pathology, medicine, biology.domesticated_animal, Animals, Epidemics, rabbit hemorrhagic disease virus type 2, European rabbit, Phylogeny, Caliciviridae Infections, General Veterinary, biology, Nucleic acid sequence, Outbreak, Note, Pulmonary edema, medicine.disease, Virology, Reverse transcription polymerase chain reaction, Emerging infectious disease, Rabbits |
| الوصف: | Twenty-three of 42 European rabbits (Oryctolagus cuniculus), belonging to the same rabbit colony, died in March 2020 (55% mortality) in Chiba prefecture, Japan. The disease course was extremely acute without indicators of death or hemorrhage. Necropsy revealed liver swelling, discoloration, cloudiness and fragility, and pulmonary edema. Histologically, severe hepatocellular necrosis (mainly peripheral) and intra-glomerular capillary hyalin thrombi were observed. On molecular-biological examination, reverse transcription polymerase chain reaction analysis of RNA from tissues detected a rabbit hemorrhagic disease virus, confirmed as a RHDV-2 VP60 fragment, which shared 99.42% nucleotide identity with the homologous fragment of RHDV-2 German isolate by nucleotide sequence analysis. This report shows the outbreak of rabbit hemorrhagic disease caused by RHDV-2, an emerging infectious disease, in Japan. |
| تدمد: | 1347-7439 0916-7250 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5df6cf29d466531bd2d5d581f3e6ca2Test https://doi.org/10.1292/jvms.21-0007Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f5df6cf29d466531bd2d5d581f3e6ca2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13477439 09167250 |
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