Cre/CysC ratio may predict muscle composition and is associated with glucose disposal ability and macrovascular disease in patients with type 2 diabetes
| العنوان: | Cre/CysC ratio may predict muscle composition and is associated with glucose disposal ability and macrovascular disease in patients with type 2 diabetes |
|---|---|
| المؤلفون: | Mei Zhang, Yanying Li, Fupeng Liu, Kejun Wang, Peng Sun, Hongshan Shen, Bo Ban, Huichao Xu, Qing Yang |
| المصدر: | BMJ Open Diabetes Research & Care, Vol 9, Iss 2 (2021) BMJ Open Diabetes Research & Care |
| بيانات النشر: | BMJ Publishing Group, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, Diseases of the endocrine glands. Clinical endocrinology, chemistry.chemical_compound, Diabetes mellitus, Internal medicine, medicine, Humans, Muscle, Skeletal, muscle weakness, Macrovascular disease, Creatinine, Integrases, biology, nutritional sciences, business.industry, diabetes complications, Muscle weakness, medicine.disease, RC648-665, Cross-Sectional Studies, Glucose, Endocrinology, Postprandial, Diabetes Mellitus, Type 2, chemistry, Cystatin C, Sarcopenia, biology.protein, Clinical care/Education/Nutrition, type 2 diabetes, medicine.symptom, business, Biomarkers |
| الوصف: | IntroductionSince the ratio of creatinine to cystatin C (Cre/CysC) can reflect muscle volume, it has been proven to be a predictor of sarcopenia in patients with or without diabetes. Here, we investigated the predictive value of Cre/CysC for the skeletal muscle composition and its correlations with glucose disposal ability and diabetic complications in patients with type 2 diabetes.Research design and methodsThe skeletal muscle index (SMI) and mean skeletal muscle attenuation (MMA) values of 193 patients with type 2 diabetes were obtained through analyses of CT images at the lumbar 3 level.ResultsSerum Cre/CysC was significantly correlated with both the SMI (r=0.375, pConclusionsCre/CysC may be a valuable predictor of skeletal muscle composition in type 2 diabetes. Patients with a higher Cre/CysC may have a better ability to dispose of postprandial glucose and are at a lower risk of macrovascular disease. |
| اللغة: | English |
| تدمد: | 2052-4897 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d9755451d98b071619799ae725d7b6Test https://drc.bmj.com/content/9/2/e002430.fullTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f2d9755451d98b071619799ae725d7b6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20524897 |
|---|