Hearing brain evaluated using near-infrared spectroscopy in congenital toxoplasmosis
| العنوان: | Hearing brain evaluated using near-infrared spectroscopy in congenital toxoplasmosis |
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| المؤلفون: | Ana Lívia Libardi Bertachini, Sergio L. Novi, Rickson C. Mesquita, Gláucia Manzan Queiroz Andrade, Gabriela Cintra Januario, Marco Aurélio Romano Silva, Débora Marques de Miranda, Luciana Macedo de Resende |
| المصدر: | Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021) Scientific Reports |
| بيانات النشر: | Nature Portfolio, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Sensory processing, Hearing loss, medicine.medical_treatment, Science, Otoacoustic emission, Sensory system, Audiology, Stimulus (physiology), Paediatric research, 050105 experimental psychology, Article, Toxoplasmosis, Congenital, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, 0501 psychology and cognitive sciences, Prospective cohort study, Hearing Loss, Multidisciplinary, Spectroscopy, Near-Infrared, business.industry, Hearing Tests, 05 social sciences, Infant, Newborn, Brain, Infant, medicine.disease, Hydrocephalus, Case-Control Studies, Diseases of the nervous system, Infectious diseases, Medicine, Female, Brainstem, medicine.symptom, business, 030217 neurology & neurosurgery, Neurological disorders |
| الوصف: | Congenital toxoplasmosis (CT) is a known cause of hearing loss directly caused by Toxoplasma gondii. Hearing loss might result from sensory, neural, or sensorineural lesions. Early treated infants rarely develop hearing loss, but retinochoroidal lesions, intracranial calcifications and hydrocephalus are common. In this study, we aimed to evaluate the brain evoked hemodynamic responses of CT and healthy infants during four auditory stimuli: mother infant directed speech, researcher infant directed speech, mother reading and researcher recorded. Children underwent Transitionally Evoked Otoacoustic Emission Auditory Testing and Automated Brainstem Auditory Response tests with normal auditory results, but with a tendency for greater latencies in the CT group compared to the control group. We assessed brain hemodynamics with functional near-infrared spectroscopy (fNIRS) measurements from 61 infants, and we present fNIRS results as frequency maps of activation and deactivation for each stimulus. By evaluating infants in the three first months of life, we observed an individual heterogeneous brain activation pattern in response to all auditory stimuli for both groups. Each channel was activated or deactivated in less than 30% of children for all stimuli. There is a need of prospective studies to evaluate if the neurologic or auditory changes course with compromise of children outcomes. |
| اللغة: | English |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2306fb9e99357e126b8299c21fcaa43Test https://doaj.org/article/a1291c582d114d60b9dc7ccc803f2744Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f2306fb9e99357e126b8299c21fcaa43 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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