Association of Apolipoprotein A1 Gene Polymorphisms with Serum Lipid Spectrum in Adolescents in East Siberia
| العنوان: | Association of Apolipoprotein A1 Gene Polymorphisms with Serum Lipid Spectrum in Adolescents in East Siberia |
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| المؤلفون: | M. A. Darenskaya, Dolgikh Vv, Sergey I. Kolesnikov, O. V. Kalyuzhnaya, T. A. Bairova, A. A. Trukhin, Lyubov Kolesnikova, O. A. Pervushina |
| المصدر: | Bulletin of Experimental Biology and Medicine. 160:267-270 |
| بيانات النشر: | Springer Science and Business Media LLC, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Male, Adolescent, Genotype, Biology, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Humans, Allele, Child, Genotyping, Gene, Alleles, Genetics, Polymorphism, Genetic, Apolipoprotein A-I, Cholesterol, Incidence (epidemiology), General Medicine, Lipids, Molecular biology, Siberia, chemistry, biology.protein, Female, Apolipoprotein A1, Restriction fragment length polymorphism |
| الوصف: | We studied the incidence of genotypes of polymorphic alleles (-75)G>A and (+83)C>T of apolipoprotein A1 gene in healthy Russian adolescents, residents of East Siberia. Genotyping was carried out by PCR with subsequent restriction fragment length polymorphism analysis. The incidence of allele (-75)A was 22.5%, of allele (+83)T - 7.3%. Association of allele (-75) A with high blood cholesterol level was revealed. |
| تدمد: | 1573-8221 0007-4888 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee74c9a74133739e3bb32419cc59eac9Test https://doi.org/10.1007/s10517-015-3146-8Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....ee74c9a74133739e3bb32419cc59eac9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15738221 00074888 |
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