Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial

التفاصيل البيبلوغرافية
العنوان: Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
المؤلفون: Florence Ouedraogo, Reshma Kailath, Amy Flaxman, Andres Noe, Rachidatou Soma, Fernando Ramos Lopez, Katie J. Ewer, Eli Rouamba, Umesh Shaligram, Jenny M. Reimer, Toussaint Rouamba, Federica Cappuccini, Ousmane Traore, Athanase M Some, Prisca Yameogo, Matthew Cairns, M Datoo, Daniel Valia, Benedict O. Orindi, Seydou Sawadogo, Sean C. Elias, Karim Derra, D Bellamy, Faizatou Sorgho, Magloire H Natama, Adrian V. S. Hill, E Mukhopadhyay, Hermann Sorgho, Innocent Valea, Alison M. Lawrie, Moubarak Tegneri, Rachel Roberts, Gregory M. Glenn, Halidou Tinto, Louis Fries, Nicola Williams
المصدر: Lancet, 397 (10287
سنة النشر: 2021
مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.medical_treatment, Population, Protozoan Proteins, Antibodies, Protozoan, 030204 cardiovascular system & hematology, law.invention, 03 medical and health sciences, 0302 clinical medicine, Immunogenicity, Vaccine, Randomized controlled trial, Adjuvants, Immunologic, Double-Blind Method, law, Internal medicine, Burkina Faso, Malaria Vaccines, parasitic diseases, medicine, Humans, 030212 general & internal medicine, Vaccines, Virus-Like Particle, Malaria, Falciparum, education, Proportional Hazards Models, education.field_of_study, Hepatitis B Surface Antigens, business.industry, Malaria vaccine, Infant, General Medicine, Saponins, Sciences bio-médicales et agricoles, Vaccine efficacy, medicine.disease, Malaria, Clinical trial, Vaccination, Treatment Outcome, Nanoparticles, Female, business, Adjuvant
الوصف: Stalled progress in controlling Plasmodium falciparum malaria highlights the need for an effective and deployable vaccine. RTS,S/AS01, the most effective malaria vaccine candidate to date, demonstrated 56% efficacy over 12 months in African children. We therefore assessed a new candidate vaccine for safety and efficacy.
info:eu-repo/semantics/published
وصف الملف: 1 full-text file(s): application/pdf; application/pdf
اللغة: English
تدمد: 0140-6736
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ce074b426a190ef5d943b4c759db00Test
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/323431Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....e8ce074b426a190ef5d943b4c759db00
قاعدة البيانات: OpenAIRE