Fluorescence diagnosis of endometriosis on the chorioallantoic membrane using 5-aminolaevulinic acid
| العنوان: | Fluorescence diagnosis of endometriosis on the chorioallantoic membrane using 5-aminolaevulinic acid |
|---|---|
| المؤلفون: | W. Böhm, A. Rück, Ch. Berg, Klaus Diedrich, E. Malik, K. Kunzi-Rapp, A. Meyhöfer-Malik |
| المصدر: | Human Reproduction. 15:584-588 |
| بيانات النشر: | Oxford University Press (OUP), 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Adult, Pathology, medicine.medical_specialty, Erythrocytes, Time Factors, Necrosis, Transplantation, Heterologous, Fimbria, Endometriosis, Neovascularization, Physiologic, Chick Embryo, Biology, Endometrium, Fluorescence, Andrology, Peritoneum, Allantois, medicine, Animals, Humans, Incubation, Rehabilitation, Obstetrics and Gynecology, Aminolevulinic Acid, medicine.disease, Transplantation, Chorioallantoic membrane, medicine.anatomical_structure, Reproductive Medicine, Female, medicine.symptom |
| الوصف: | The chorioallantoic membrane (CAM) is a useful model for the fluorescence diagnosis of experimentally induced endometriosis. In our experimental setup 75.7% of the histologically examined tissue preparations were viable and only 24.3% showed signs of necrosis on the CAM after various periods of incubation. Best results were obtained when grafting to the CAM was performed between days 7 and 9 and when implants were left on the CAM for 3-5 days (P < 0.05). We were able to demonstrate that 5-aminolaevulinic acid (ALA) is stored selectively in ectopic endometrium. The subsequent fluorescence of the endometrium shows a rapid increase that reaches a peak after 10-14 h which can be clearly differentiated from the weaker fluorescence of grafted normal peritoneum and fimbriae (P < 0.01). |
| تدمد: | 1460-2350 0268-1161 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bb4060f3ad9c3544eec4b858a4f719Test https://doi.org/10.1093/humrep/15.3.584Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e8bb4060f3ad9c3544eec4b858a4f719 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14602350 02681161 |
|---|