Predictors of the maximal oxygen consumption in adult patients with type 1 diabetes treated with personal insulin pumps
| العنوان: | Predictors of the maximal oxygen consumption in adult patients with type 1 diabetes treated with personal insulin pumps |
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| المؤلفون: | Tomasz Klupa, Tomasz Pałka, Maciej T. Malecki, Łukasz Tota, Małgorzata Morawska, Sandra Mrozinska, Beata Kieć-Wilk, Bartłomiej Matejko |
| المصدر: | Journal of Diabetes Investigation Journal of Diabetes Investigation, Vol 12, Iss 8, Pp 1377-1385 (2021) |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Blood Glucose, Male, Anaerobic Threshold, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Body fat percentage, Running, Cohort Studies, 0302 clinical medicine, Surveys and Questionnaires, Type 1 diabetes, Insulin, 030212 general & internal medicine, Meals, Adiposity, Sex Characteristics, VO2 max, Articles, General Medicine, Clinical Science and Care, Original Article, Female, Adult, Insulin pump, medicine.medical_specialty, 030209 endocrinology & metabolism, Diseases of the endocrine glands. Clinical endocrinology, Young Adult, 03 medical and health sciences, Insulin Infusion Systems, Predictive Value of Tests, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Lactic Acid, Cardiorespiratory fitness, Glycemic, Glycated Hemoglobin, Physical activity, business.industry, Blood Glucose Self-Monitoring, RC648-665, medicine.disease, Diabetes Mellitus, Type 1, Physical Fitness, business, Stress, Psychological |
| الوصف: | Aims/Introduction Regular physical activity for adults with type 1 diabetes mellitus improves cardiorespiratory fitness (CF) and quality of life. The aim of our study was to evaluate clinical and biochemical features that might be associated with CF in a homogenous group of adults with type 1 diabetes mellitus who are all treated with a personal insulin pump (continuous subcutaneous insulin infusion). Materials and Methods We assessed CF in 62 patients (74.2% of whom were men) who fulfilled the eligibility criteria. To determine maximal oxygen consumption, the march‐running test on the treadmill was carried out. Two hours before the test, the patients consumed a defined meal covered by a dose of rapid acting insulin analog that was reduced by 25% from their regular dose. Basal insulin infusion was reduced by 50% for an hour. Additionally, the Perceived Stress Scale‐10 questionnaire was used to measure the perception of stress. Results There was no episode of severe hypoglycemia during or after the test. In the final model, independent predictors of maximal oxygen consumption were sex, body fat percentage, lactate at 20 min after CF test and Perceived Stress Scale‐10 score. Of interest, neither short‐term (continuous glucose monitoring) nor long‐term (glycosylated hemoglobin) metabolic control parameters were predictors of CF. Conclusions In our selected homogenous group of patients with type 1 diabetes mellitus treated with personal insulin pumps, higher CF was associated with a lower percentage of body fat, male sex, higher lactate level after the CF test and the Perceived Stress Scale‐10 score. The proposed protocol in our cohort proved to be safe with regard to glycemic control. Higher cardiorespiratory fitness (CF) was associated with a lower percentage of body fat, male sex, higher lactate level after the CF test and a Perceived Stress Scale‐10 score. Neither short‐term (continuous glucose monitoring) nor long‐term (glycosylated hemoglobin) metabolic control parameters were predictors of CF. We presented a simple protocol for carrying out CF tests which proved to be safe with regard to glycemic control in our cohort. |
| تدمد: | 2040-1124 2040-1116 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e872120d765f4f2c176dd850e4d51ca3Test https://doi.org/10.1111/jdi.13490Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e872120d765f4f2c176dd850e4d51ca3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20401124 20401116 |
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