Developing a new endograft for the treatment of juxtarenal aortic aneurysms: definition and experimentation
| العنوان: | Developing a new endograft for the treatment of juxtarenal aortic aneurysms: definition and experimentation |
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| المؤلفون: | Luiz Lanzaiotti, Sergio Quilici Belczak, Erasmo Simão da Silva, Nelson De Luccia, Pedro Puech-Leão, Ricardo Aun, Yuri Botelho |
| المصدر: | Clinics, Vol 70, Iss 6, Pp 435-440 (2015) Clinics Clinics; v. 70 n. 6 (2015); 435-440 Clinics; Vol. 70 Núm. 6 (2015); 435-440 Clinics; Vol. 70 No. 6 (2015); 435-440 Universidade de São Paulo (USP) instacron:USP Clinics, Volume: 70, Issue: 6, Pages: 435-440, Published: JUN 2015 |
| بيانات النشر: | Elsevier BV, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | medicine.medical_specialty, Swine, medicine.medical_treatment, Pilot Projects, Prosthesis Design, Endovascular aneurysm repair, Blood Vessel Prosthesis Implantation, Aortic aneurysm, Renal Artery, Blood vessel prosthesis, medicine.artery, medicine, Animals, Humans, EVAR, cardiovascular diseases, Superior mesenteric artery, Renal artery, Aorta, lcsh:R5-920, Pericardial patch, business.industry, Endovascular Procedures, General Medicine, Juxtarenal aneurysm, Clinical Science, medicine.disease, Blood Vessel Prosthesis, Surgery, Models, Animal, cardiovascular system, Cattle, Stents, Juxtarenal aortic abdominal aneurysm, Radiology, lcsh:Medicine (General), business, Neck, Aortic Aneurysm, Abdominal |
| الوصف: | OBJECTIVES: To analyze angiotomographic parameters of juxtarenal aneurysms to assess the applicability of an endograft model to patients and to create in vitro and in vivo models to assess the new endograft. METHODS: A total of 49 patients with juxtarenal aneurysms were submitted to angiotomographic evaluation, and parameters such as the aortic diameter, the length of the neck, and the angulations of the celiac trunk, superior mesenteric artery and renal arteries; the distances between them; and anatomic variations were analyzed. Based on these parameters, an endograft model was developed and tested in a newly created in vitro model of juxtarenal aneurysm. An experimental model of juxtarenal aneurysm was then established in six pigs weighing 50-60 kg to assess the new endograft model. RESULTS: The angiotomographic parameters of juxtarenal aneurysm measured in this study were similar to those reported in the literature and allowed the development of an endograft based on the hourglass concept, which was applicable to 85.8% of the patients. The in vitro model of juxtarenal aneurysm evidenced good radiopacity and functionality and permitted adjustments in the new device and technical improvements in the procedures for treating these aneurysms. In addition, the porcine model of juxtarenal aneurysm was successfully created in all six animals using a bovine pericardial patch, and use of the new endograft in three pilot procedures evidenced its feasibility. CONCLUSIONS: The Hourglass endograft was rendered applicable to treatment of the majority of patients with juxtarenal aneurysms simply by changing its diameter. Moreover, the new in vitro and in vivo models were shown to be effective for assessing both the presented endograft and experiments assessing the endovascular treatment of juxtarenal aneurysms. |
| وصف الملف: | application/pdf; text/html |
| تدمد: | 1807-5932 1980-5322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bdc152170fb5a8dabf001dad8cfa80Test https://doi.org/10.6061/clinics/2015Test(06)09 |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e4bdc152170fb5a8dabf001dad8cfa80 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18075932 19805322 |
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