Purpose To detect the findings of optical coherence tomography angiography (OCTA) in eyes with central serous chorioretinopathy (CSCR), in comparison with conventional multimodal imaging. Patients and methods In the current case series, 80 eyes of 80 patients were diagnosed to have CSCR, and they underwent spectral domain optical coherence tomography (SD-OCT), fluorescein angiography (FA), and OCTA. OCTA images are performed at two main depth intervals: automatically segmented outer retina and automatically segmented choriocapillaris. Results In 40 of 80 eyes, OCTA images showed detached retina adjacent to the leakage point, compared with 40 of 80 eyes using FA, and 80 of 80 eyes using SD-OCT. In 44 of 80 eyes, irregular flow patterns were observed on OCTA images through the choriocapillaris. OCTA images could not identify leakage points in any of the included eyes, compared with 68 of 80 eyes on FA, and 56 of 80 eyes on SD-OCT. In 12 of 80 eyes, abnormal vessels (associated choroidal neovascularization) were observed on OCTA images, compared with eight of 80 eyes in SD-OCT and four of 80 eyes in FA. Conclusion OCTA images of the superficial and deep retinal plexus, outer retina, and choriocapillaris did not reveal altered flow patterns directly associated with the leakage point in acute CSCR. However, OCTA was able to visualize altered choroidal flow in some of the included eyes and was the best between all other modalities in detection of choroidal neovascularization in eyes with chronic CSCR.
