Elevated Circulating TNF-α in Fat-Free Mass Non-Responders Compared to Responders Following Exercise Training in Older Women
| العنوان: | Elevated Circulating TNF-α in Fat-Free Mass Non-Responders Compared to Responders Following Exercise Training in Older Women |
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| المؤلفون: | Gordon Fisher, Gary R. Hunter, C. Scott Bickel |
| المصدر: | Biology Biology, Vol 3, Iss 3, Pp 551-559 (2014) |
| بيانات النشر: | MDPI, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Project Report, medicine.medical_specialty, combined exercise training, General Immunology and Microbiology, Inflammation, Biology, Gastroenterology, elderly, General Biochemistry, Genetics and Molecular Biology, Proinflammatory cytokine, Fat mass, Muscle hypertrophy, Non responders, lcsh:Biology (General), Fat free mass, inflammation, Internal medicine, Group interaction, medicine, Aerobic exercise, medicine.symptom, General Agricultural and Biological Sciences, hypertrophy, lcsh:QH301-705.5 |
| الوصف: | The purpose of this investigation was to determine if differences in inflammatory cytokines exist between fat-free mass responders versus non-responders following a combined resistance/aerobic training program in older women. Fifty women over 60 years old, mean BMI 27 ± 4 (kg/m2) and physically untrained, participated in a combined training program for 16-weeks. Body composition, muscle strength, and serum inflammatory markers (TNF-α, CRP, and IL-6) were assessed at baseline and 16-weeks post-training. A significant time effect was observed for weight, %fat, fat mass, and all strength measures (p < 0.05). A group interaction was observed for TNF-α (p < 0.05), which revealed higher concentrations of circulating TNF-α at baseline (18%) and post-exercise training (24%) in non-responders compared to responders (p < 0.05). In conclusion, this study revealed a significantly greater concentration of circulating TNF-α in older women that do not increase fat-free mass following training. |
| اللغة: | English |
| تدمد: | 2079-7737 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cd17b315cab6cca7f68f1dcb1dbd85Test http://europepmc.org/articles/PMC4192627Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e2cd17b315cab6cca7f68f1dcb1dbd85 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20797737 |
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