Access to Imidazolidines via 1,3-Dipolar Cycloadditions of 1,3,5-Triazinanes with Aziridines
| العنوان: | Access to Imidazolidines via 1,3-Dipolar Cycloadditions of 1,3,5-Triazinanes with Aziridines |
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| المؤلفون: | Yongsheng Zheng, Zheng-Hui Li, Liang Tu, Jing Li, Ji-Kai Liu, Shuyan Yu, Tao Feng, Wen-Xuan Wang, Rong Huang |
| المصدر: | The Journal of Organic Chemistry. 84:11161-11169 |
| بيانات النشر: | American Chemical Society (ACS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | chemistry.chemical_compound, Nucleophile, chemistry, 010405 organic chemistry, Imidazolidine, Organic Chemistry, 010402 general chemistry, Ring (chemistry), Imidazolidines, 01 natural sciences, Combinatorial chemistry, Cycloaddition, 0104 chemical sciences |
| الوصف: | The unprecedented 1,3-dipolar cycloaddition of 1,3,5-triazinanes and aziridines has been described. With readily available starting material, this method offers efficient access to a wide range of functionalized imidazolidine derivatives in moderate to good yields (up to 92%) under mild conditions. Preliminary mechanistic investigations show that the ring opened zwitterionic pathway product dominated over the second-order nucleophilic substitution-like product. This protocol is very promising because the reaction is scalable, and gives versatile transformation of the products into other functionalized imidazolidines. |
| تدمد: | 1520-6904 0022-3263 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e264af6e6edd2bf2339fc16ebf0a496eTest https://doi.org/10.1021/acs.joc.9b01959Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....e264af6e6edd2bf2339fc16ebf0a496e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15206904 00223263 |
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