Lipid-Modified Peptide Nucleic Acids:Synthesis and Application to Programmable Liposome Fusion
| العنوان: | Lipid-Modified Peptide Nucleic Acids:Synthesis and Application to Programmable Liposome Fusion |
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| المؤلفون: | Philipp M. G. Löffler, Stefan Vogel, Alexander Rabe |
| المساهمون: | Nielsen, Peter E. |
| المصدر: | Löffler, P M G, Rabe, A & Vogel, S 2020, Lipid-Modified Peptide Nucleic Acids : Synthesis and Application to Programmable Liposome Fusion . in P E Nielsen (ed.), Peptide Nucleic Acids . vol. 2105, Methods in molecular biology (Clifton, N.J.), pp. 75-96 . https://doi.org/10.1007/978-1-0716-0243-0_5Test Peptide Nucleic Acids ISBN: 9781071602423 |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Liposome, education.field_of_study, Lipidated PNA, Population, Phospholipid, Lipid bilayer fusion, Peptide, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Fluorescence, 0104 chemical sciences, Content mixing assays, chemistry.chemical_compound, chemistry, Liposomes, Biophysics, Nucleic acid, Surface modification, 0210 nano-technology, education |
| الوصف: | Peptide nucleic acids (PNAs) can be modified with aliphatic lipid chains and designed to be water soluble and able to spontaneously insert into phospholipid bilayers. Liposomes with 1.5% negatively charged POPG can be driven to fuse and mix their inner content volumes via functionalization with such lipidated peptide nucleic acids (LiPNAs). During fusion, only low amounts of leakage occur ( |
| اللغة: | English |
| ردمك: | 978-1-07-160242-3 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfc2795f702d7ce8605f98446770766Test https://portal.findresearcher.sdu.dk/da/publications/8b126417-7bb6-48be-8ae9-f4aa2acf4b6cTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....dcfc2795f702d7ce8605f98446770766 |
| قاعدة البيانات: | OpenAIRE |
| ردمك: | 9781071602423 |
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