Characteristics of Adult Patients with Idiopathic Retroperitoneal Fibrosis and Assessment of Risk of Relapse at Diagnosis
| العنوان: | Characteristics of Adult Patients with Idiopathic Retroperitoneal Fibrosis and Assessment of Risk of Relapse at Diagnosis |
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| المؤلفون: | Sébastien Humbert, Philip Bielefeld, Nadine Magy-Bertrand, Bastien Bouldoires, Bernard Bonnotte, Veronique Fournier, Jerome Razanamahery, Gilles Blaison |
| المصدر: | Journal of Clinical Medicine, Vol 10, Iss 1380, p 1380 (2021) Journal of Clinical Medicine Volume 10 Issue 7 |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, medicine.medical_treatment, risk of relapse, lcsh:Medicine, 030204 cardiovascular system & hematology, Retroperitoneal fibrosis, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, idiopathic retroperitoneal fibrosis, medicine, Relapse risk, Idiopathic Retroperitoneal Fibrosis, 030203 arthritis & rheumatology, Adult patients, business.industry, lcsh:R, General Medicine, medicine.disease, smoking cessation, Radiological weapon, Smoking cessation, Chronic renal failure, medicine.symptom, business, Infiltration (medical) |
| الوصف: | Objectives: To compare adult patients’ characteristics suffering from idiopathic retroperitoneal fibrosis between “relapse-free” and relapsing patients at the diagnosis and identify factors associated with relapse at initial presentation. Methods: We conducted a retrospective multicentric study in four hospitals in Eastern France, from 1993 to 2020, of adult patients suffering from idiopathic retroperitoneal fibrosis. We analyzed clinical, biological, and radiological features at diagnosis and during a forty-month follow-up. Results: Of 47 patients suffering from retroperitoneal fibrosis, 21 patients had idiopathic retroperitoneal fibrosis. Among them, 13 experienced one or more relapses during follow-up. At diagnosis, clinical characteristics, relevant comorbidities, biological and radiological features were similar between groups. Smoking cessation seems associated with decreased relapse risk (p: 0.0624). A total of 8 patients developed chronic renal failure during follow-up. Ureteral infiltration at diagnosis was associated with evolution to chronic renal failure (p: 0.0091). Conclusion: No clinical, biological, or radiological features could predict relapse at retroperitoneal fibrosis diagnosis, but smoking cessation may prevent relapse. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2077-0383 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db35978e607b17b39e61f6ee728f30a8Test https://www.mdpi.com/2077-0383/10/7/1380Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....db35978e607b17b39e61f6ee728f30a8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20770383 |
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