Brainstem dysfunction in critically ill patients
| العنوان: | Brainstem dysfunction in critically ill patients |
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| المؤلفون: | Aurélien Mazeraud, Tarek Sharshar, Jan Claassen, Eric Azabou, Sarah Benghanem, Cassia Righy Shinotsuka, Benjamin Rohaut, Vibol Chhor |
| المساهمون: | CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Medical Intensive Care Unit [Paris] (Medical-ICU), AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Neurological Intensive Care Unit [Paris] (Neuro-ICU), Université Paris Descartes - Paris 5 (UPD5)-Groupe Hospitalier Universitaire Paris (GHU-Paris), Neuropathologie expérimentale - Experimental neuropathology, Institut Pasteur [Paris] (IP)-Université Paris Descartes - Paris 5 (UPD5), Hôpital Raymond Poincaré [AP-HP], Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Department of Intensive Care Medicine [Paris], Centre hospitalier Saint-Joseph [Paris], Intensive Care Unit and Postgraduate Program [Rio de Janeiro, Brésil], Instituto Nacional de Câncer [Rio de Janeiro, Brésil], D'Or Institute for Research and Education [Rio de Janeiro], Department of Neurology [New York, NY, États-Unis], Neurological Intensive Care Unit [New York, NY, États-Unis] (Neuro-ICU), Columbia University [New York]-Columbia University [New York], Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Bodescot, Myriam, Institut Pasteur [Paris]-Université Paris Descartes - Paris 5 (UPD5), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | Critical Care Critical Care, 2020, 24 (1), pp.5. ⟨10.1186/s13054-019-2718-9⟩ Critical Care, BioMed Central, 2020, 24 (1), pp.5. ⟨10.1186/s13054-019-2718-9⟩ Critical Care, Vol 24, Iss 1, Pp 1-14 (2020) |
| بيانات النشر: | BioMed Central, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Brainstem reflexes, Neurological respiratory failure, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Critical Illness, Disorders of consciousness, Review, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, medicine, otorhinolaryngologic diseases, Autonomic nervous system, Humans, Intensive care unit, Glasgow Coma Scale, Auditory and somatosensory evoked potentials and electroencephalogram, Brain injured patients, Immune reflex, business.industry, Cranial nerves, lcsh:Medical emergencies. Critical care. Intensive care. First aid, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Dysautonomia, Brain, 030208 emergency & critical care medicine, lcsh:RC86-88.9, medicine.disease, Spinal cord, Prognosis, medicine.anatomical_structure, Autonomic Nervous System Diseases, Sedation, Brainstem dysfunction, Brainstem, medicine.symptom, business, Respiratory Insufficiency, Neuroscience, Reticular activating system, 030217 neurology & neurosurgery, Neuroanatomy, Brain Stem |
| الوصف: | The brainstem conveys sensory and motor inputs between the spinal cord and the brain, and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions via the ascending reticular activating system and the autonomic nuclei, respectively. Brainstem dysfunction may lead to sensory and motor deficits, cranial nerve palsies, impairment of consciousness, dysautonomia, and respiratory failure. The brainstem is prone to various primary and secondary insults, resulting in acute or chronic dysfunction. Of particular importance for characterizing brainstem dysfunction and identifying the underlying etiology are a detailed clinical examination, MRI, neurophysiologic tests such as brainstem auditory evoked potentials, and an analysis of the cerebrospinal fluid. Detection of brainstem dysfunction is challenging but of utmost importance in comatose and deeply sedated patients both to guide therapy and to support outcome prediction. In the present review, we summarize the neuroanatomy, clinical syndromes, and diagnostic techniques of critical illness-associated brainstem dysfunction for the critical care setting. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1466-609X 1364-8535 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf7203ac10ef5266e6f1c040d4ac6caTest http://europepmc.org/articles/PMC6945639Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....daf7203ac10ef5266e6f1c040d4ac6ca |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1466609X 13648535 |
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