Principles and frequency of self-adjustment of insulin dose in people with diabetes mellitus type 1 and correlation with markers of metabolic control

التفاصيل البيبلوغرافية
العنوان: Principles and frequency of self-adjustment of insulin dose in people with diabetes mellitus type 1 and correlation with markers of metabolic control
المؤلفون: Thomas Lehmann, Nadine Kuniss, Stefan Lorkowski, Guido Kramer, Christof Kloos, Ulrich A. Müller, Nicolle Müller, Gunter Wolf
المصدر: Diabetes research and clinical practice. 116
سنة النشر: 2016
مصطلحات موضوعية: Research design, Adult, Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, medicine.medical_treatment, 030209 endocrinology & metabolism, Hypoglycemia, Correlation, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Insulin, Drug Dosage Calculations, 030212 general & internal medicine, media_common, Aged, Glycated Hemoglobin, business.industry, General Medicine, Middle Aged, medicine.disease, Surgery, Self Care, Diabetes Mellitus, Type 1, Feeling, Metabolic control analysis, Physical therapy, Female, business, Biomarkers, Social status
الوصف: Objective Insulin dose self-adjustment (ISA) to different blood glucose levels, carbohydrate intake, exercise or illness is a core element of structured education programmes for people with diabetes mellitus type 1 (DM1). The aim of this study was to register the patients’ current principles and frequency of ISA and to check the ability for correct adjustments. Research design and methods 117 people with DM1 (mean HbA 1c 7.1%, diabetes duration 24 y) were interviewed in a tertiary care centre. The number of ISA was drawn from the last 28 days of the patients’ diary. The ability to find the correct insulin dose was assessed using five different calculation examples. All patients had participated in a structured education programme. Results Mean frequency of ISA was 72.1 ± 29.4 per 28 days. ISA by adjustment rules was used in 48% (56/117) and by personal experience or feeling in 44% (52/117). Patients adjusting by feeling were older, did less ISA and had lower social status. There were no differences in HbA 1c (feeling 7.2 ± 0.8 vs . rules 7.0 ± 0.9, p = 0.403), non severe hypoglycaemia (feeling 1.7 ± 1.8 vs . rules 1.9 ± 1.9, p = 0.132) and comprehensibility of ISA between both groups. Overall, the participants answered on average 2.8 ± 2.3 of the five calculation examples correctly. Conclusions Although all people were trained to use a factor for correction for ISA in case of high premeal blood glucose levels, only half of the patients adjusted their insulin dosage using the complex rules from the treatment and education programme. Patients, who performed their ISA based upon feeling, did not show worse metabolic control.
تدمد: 1872-8227
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f2a66f72520cfea402713f6cc2cebbTest
https://pubmed.ncbi.nlm.nih.gov/27321348Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....d8f2a66f72520cfea402713f6cc2cebb
قاعدة البيانات: OpenAIRE