Performance of a Multidisciplinary Pancreatic Cancer Conference in Predicting and Managing Resectable Pancreatic Cancer
| العنوان: | Performance of a Multidisciplinary Pancreatic Cancer Conference in Predicting and Managing Resectable Pancreatic Cancer |
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| المؤلفون: | Alexander V. Kirichenko, Donald Atkinson, Harry Williams, Suzanne Morrissey, Abhijit Kulkarni, Shailendra Singh, Manav Sharma, Ghita Moussiade, Aslam Syed, Shyam Thakkar, Marcia Mitre, Bharat Rao, Mrinal Garg, Abhishek Gulati, Manish Dhawan, Amy Tang, Suzanne Schiffman, Anthony Lupetin, Dulabh Monga |
| المصدر: | Pancreas. 48:80-84 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, Resectable Pancreatic Cancer, medicine.medical_specialty, Pancreatic ductal adenocarcinoma, Consensus Development Conferences as Topic, Endocrinology, Diabetes and Metabolism, Stage ii, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, Endocrinology, Pancreatic cancer, Outcome Assessment, Health Care, Internal Medicine, Carcinoma, medicine, Humans, Prospective Studies, Stage (cooking), Prospective cohort study, Aged, Hepatology, Tumor size, business.industry, Middle Aged, Prognosis, medicine.disease, Pancreatic Neoplasms, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, Radiology, business, Carcinoma, Pancreatic Ductal |
| الوصف: | Objectives Surgery is the curative treatment for pancreatic ductal adenocarcinoma (PDA). Guidelines recommend utilizing a multidisciplinary pancreatic cancer conference (MDPC) in treatment; however, data are limited. The objective of this study was to assess the accuracy of an MDPC. Methods Patients with PDA presented at an MDPC were prospectively collected from April 2013 to August 2016. Patients were included if the MDPC predicted them to have resectable PDA and underwent upfront surgery. Secondary aims were to compare differences in tumor characteristics, time to surgery, and resection rates with patients prior to MDPC implementation (pre-MDPC). Results A total of 278 patients were presented at the MDPC. After excluding borderline and nonresectable cases, 91 patients were predicted as resectable on evaluation, and 70 were fit for surgery. The MDPC predicted resection in 91.4%. The MDPC had larger tumor size (32.6 vs 24.0 mm), greater proportion of stage II tumor, and a shorter time from diagnosis to resection (27.3 vs 35.5 days) compared with the pre-MDPC. Microscopically negative resections were similar between MDPC and pre-MDPC (85.9% vs 88.0%) despite advanced tumor size and stage. Conclusions The MDPC demonstrates a high resection rate. Compared with a pre-MDPC, MDPC provides shorter time to surgery and selects for advanced tumors. |
| تدمد: | 1536-4828 0885-3177 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c2061c98545947b138ea6895253a1cTest https://doi.org/10.1097/mpa.0000000000001209Test |
| رقم الانضمام: | edsair.doi.dedup.....d6c2061c98545947b138ea6895253a1c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15364828 08853177 |
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