Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection
| العنوان: | Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection |
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| المؤلفون: | Paula Abal, Mercedes R. Vieytes, M. Carmen Louzao, Cristina Carrera, Luis M. Botana, Natalia Vilariño, Eva Cagide |
| المساهمون: | Centro Interdisciplinar de Investigação Marinha e Ambiental |
| المصدر: | Toxins Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP Toxins, Vol 10, Iss 8, p 324 (2018) |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Ciguatoxin, Health, Toxicology and Mutagenesis, lcsh:Medicine, Poison control, Review, acute toxicity, Toxicology, medicine.disease_cause, biotoxin, 03 medical and health sciences, intoxication, Environmental health, Okadaic Acid, Medicine, Animals, Humans, Shellfish Poisoning, Spiro Compounds, Chronic toxicity, Acrylamides, toxicity equivalency factor, business.industry, Toxin, lcsh:R, Acute intoxication, Consumer protection, Acute toxicity, 3. Good health, 030104 developmental biology, 13. Climate action, Marine Toxins, business, Marine toxin, chronic toxicity |
| الوصف: | Marine biotoxins are produced by aquatic microorganisms and accumulate in shellfish or finfish following the food web. These toxins usually reach human consumers by ingestion of contaminated seafood, although other exposure routes like inhalation or contact have also been reported and may cause serious illness. This review shows the current data regarding the symptoms of acute intoxication for several toxin classes, including paralytic toxins, amnesic toxins, ciguatoxins, brevetoxins, tetrodotoxins, diarrheic toxins, azaspiracids and palytoxins. The information available about chronic toxicity and relative potency of different analogs within a toxin class are also reported. The gaps of toxicological knowledge that should be studied to improve human health protection are discussed. In general, gathering of epidemiological data in humans, chronic toxicity studies and exploring relative potency by oral administration are critical to minimize human health risks related to these toxin classes in the near future. Support from the following FEDER cofunded-grants. From Conselleria de Cultura, Educacion e Ordenación Universitaria Xunta de Galicia, 2017 GRC GI-1682 (ED431C 2017/01). From CDTI and Technological Funds, supported by Ministerio de Economía, Industria y Competitividad, AGL2014-58210-R, AGL2016-78728-R (AEI/FEDER, UE), ISCIII/PI16/01830 and RTC-2016-5507-2, ITC-20161072. From European Union POCTEP 0161-Nanoeaters -1-E-1, Interreg AlertoxNet EAPA-317-2016, and H2020 778069-EMERTOX. |
| وصف الملف: | application/pdf |
| تدمد: | 2072-6651 |
| DOI: | 10.3390/toxins10080324 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1611856f3db909ce7ee6b7760d3264eTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d1611856f3db909ce7ee6b7760d3264e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726651 |
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| DOI: | 10.3390/toxins10080324 |