Feasibility Randomized Trial for an Intensive Memory-Focused Training Program for School-Aged Children with Acquired Brain Injury
| العنوان: | Feasibility Randomized Trial for an Intensive Memory-Focused Training Program for School-Aged Children with Acquired Brain Injury |
|---|---|
| المؤلفون: | Andrea Nordio, Marc Modat, Sandra Strazzer, Susanna Galbiati, Filippo Arrigoni, Monica Recla, Erika Molteni, Valentina Pastore, Valentina Manfredi |
| المصدر: | Brain Sciences, Vol 10, Iss 430, p 430 (2020) Brain Sciences; Volume 10; Issue 7; Pages: 430 Brain Sciences |
| بيانات النشر: | MDPI AG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | pediatric brain injury, child, memory, rehabilitation, immediate and delayed recall, left inferior frontal gyrus, 050103 clinical psychology, medicine.medical_specialty, medicine.medical_treatment, Brain tumor, Pediatric acquired brain injury, Article, law.invention, lcsh:RC321-571, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, medicine, 0501 psychology and cognitive sciences, Acquired brain injury, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Rehabilitation, business.industry, General Neuroscience, 05 social sciences, Neuropsychology, medicine.disease, Clinical trial, Cognitive remediation therapy, Physical therapy, business, 030217 neurology & neurosurgery |
| الوصف: | (1) Background: Memory deficits are common sequelae of pediatric Acquired Brain Injury (ABI). Only methods for non-focused cognitive remediation are available to the pediatric field. The aims of this feasibility trial are the description, implementation, and test of an intensive program specific to the training and re-adaptation of memory function in children, called Intensive Memory-Focused Training Program (IM-FTP); (2) Methods: Eleven children and adolescents with ABI (mean age at injury = 12.2 years, brain tumor survivors excluded) were clinically assessed and rehabilitated over 1-month through IM-FTP, including physio-kinesis/occupational, speech, and neuropsychology treatments. Each patient received a psychometric evaluation and a brain functional MRI at enrollment and at discharge. Ten pediatric controls with ABI (mean age at injury = 13.8 years) were clinically assessed, and rehabilitated through a standard program; (3) Results: After treatment, both groups had marked improvement in both immediate and delayed recall. IM-FTP was associated with better learning of semantically related and unrelated words, and larger improvement in immediate recall in prose memory. Imaging showed functional modification in the left frontal inferior cortex; (4) Conclusions: We described an age-independent reproducible multidisciplinary memory-focused rehabilitation protocol, which can be adapted to single patients while preserving inter-subject comparability, and is applicable up to a few months after injury. IM-FTP will now be employed in a powered clinical trial. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2076-3425 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf799815f06d0fdbeb0635a62b4e1d8aTest https://www.mdpi.com/2076-3425/10/7/430Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....cf799815f06d0fdbeb0635a62b4e1d8a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20763425 |
|---|