Variability in Serum Creatine Kinase Response After Eccentric Exercise of the Elbow Flexors
| العنوان: | Variability in Serum Creatine Kinase Response After Eccentric Exercise of the Elbow Flexors |
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| المؤلفون: | Kazunori Nosaka, Priscilla M. Clarkson |
| المصدر: | International Journal of Sports Medicine. 17:120-127 |
| بيانات النشر: | Georg Thieme Verlag KG, 1996. |
| سنة النشر: | 1996 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Movement, Elbow, Aspartate transaminase, Physical Therapy, Sports Therapy and Rehabilitation, Isometric exercise, chemistry.chemical_compound, Internal medicine, Lactate dehydrogenase, Elbow Joint, medicine, Humans, Eccentric, Orthopedics and Sports Medicine, Muscle, Skeletal, Creatine Kinase, biology, Myoglobin, business.industry, Blood Proteins, Anatomy, Magnetic Resonance Imaging, medicine.anatomical_structure, Endocrinology, chemistry, biology.protein, Creatine kinase, medicine.symptom, business, Muscle contraction |
| الوصف: | There is a large inter-subject variability in serum creatine kinase (CK) response after eccentric exercise. This study examined and compared the variability of CK activity, other serum protein increases (aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, aldolase, myoglobin),changes in muscle damage indicators (maximal isometric force: MIF, relaxed and flexed elbow joint angle: RANG and FANG, circumference: CIR, and muscle soreness level: SOR), and changes in magnetic resonance (MR) images. Ten male subjects (21.7 +/- 1.6 yrs) performed 24 maximal eccentric actions of the elbow flexors, and measurements except MR images were taken immediately before and after, and for 10 days after exercise. MR images were taken 7 days after exercise. A large variability in peak CK response (236 - 25,244 IU.I(-1) was found among subjects. Spearman rank-order correlation coefficients (r) revealed significant correlations of peak CK with peak serum protein levels (r = 0.79-0.95), peak changes in MIF (r = 0.73-0.79), RANG (r = 0.69), and CIR (r = 0.91). The higher the peak CK levels, the more profound the abnormality in the MR images and the larger the changes in MR signal intensity (r = 0.90-0.94). It is concluded that the large variability in CK response after exercise seems to be related to the variability in exercise-induced muscle damage. |
| تدمد: | 1439-3964 0172-4622 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc80d6a538f64f581760c0b1adc6dd99Test https://doi.org/10.1055/s-2007-972819Test |
| رقم الانضمام: | edsair.doi.dedup.....cc80d6a538f64f581760c0b1adc6dd99 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14393964 01724622 |
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