PDL-1 expression in lung carcinoma and its correlation with clinicopathological and prognostic characteristics
| العنوان: | PDL-1 expression in lung carcinoma and its correlation with clinicopathological and prognostic characteristics |
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| المؤلفون: | Alyaa R Elsergany, Tamer Elhadidy, Mayada S Farrag, Eman M. Ibrahim, Heba Wagih Abdelwahab |
| المصدر: | Journal of Immunoassay and Immunochemistry. 42:679-690 |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Lung Neoplasms, animal diseases, medicine.medical_treatment, Clinical Biochemistry, Immunology, chemical and pharmacologic phenomena, Adenocarcinoma, 01 natural sciences, B7-H1 Antigen, Correlation, Immune system, Carcinoma, Non-Small-Cell Lung, Biomarkers, Tumor, Carcinoma, Humans, Immunology and Allergy, Medicine, Lung cancer, Lung, business.industry, 010401 analytical chemistry, High mortality, Immunotherapy, biochemical phenomena, metabolism, and nutrition, Prognosis, medicine.disease, 0104 chemical sciences, ErbB Receptors, Medical Laboratory Technology, medicine.anatomical_structure, Cancer research, bacteria, High incidence, business |
| الوصف: | Lung cancers have high incidence and high mortality rates. The immune checkpoints as programmed death ligand 1 (PDL-1) can suppress the tumor immune reaction. So, their blocking seems to be a way to treat tumors. This study assesses PDL-1 immunohistochemical expression in lung cancer, and its correlation with prognosis. It included 62 specimens of lung cancer in Hospitals of Mansoura Faculty of Medicine, Egypt. Seventy-one percent of cases showed positive PDL-1 and about 59.1% of them showed high expression. PDL-1 expression in NSCLC was significantly higher than in SCLC ( |
| تدمد: | 1532-4230 1532-1819 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba655b4844421ee73175c75d4611545Test https://doi.org/10.1080/15321819.2021.1938606Test |
| رقم الانضمام: | edsair.doi.dedup.....cba655b4844421ee73175c75d4611545 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15324230 15321819 |
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